Functional and Oncological Outcomes of Open Partial Laryngectomy vs. Transoral Laser Surgery in Supraglottic Larynx Cancer
Objective: The aim of the presented study was to evaluate the outcomes of open partial laryngectomy (OPL) versus transoral laser surgery (TLS) in patients operated on for supraglottic laryngeal carcinoma based on functional parameters (duration of hospitalization, oral nutritional status and duratio...
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| Format: | Article |
| Language: | English |
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Galenos Yayincilik
2020-12-01
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| Series: | Turkish Archives of Otorhinolaryngology |
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http://turkarchotolaryngol.net/archives/archive-detail/article-preview/functional-and-oncological-outcomes-of-open-partia/43861
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| _version_ | 1828027558315163648 |
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| author | Muhammet Fatih Gökmen Zahide Çiler Büyükatalay Süha Beton Mustafa Kürşat Gökcan Gürsel Dursun Cem Meço Tarık Babür Küçük |
| author_facet | Muhammet Fatih Gökmen Zahide Çiler Büyükatalay Süha Beton Mustafa Kürşat Gökcan Gürsel Dursun Cem Meço Tarık Babür Küçük |
| author_sort | Muhammet Fatih Gökmen |
| collection | DOAJ |
| description | Objective: The aim of the presented study was to evaluate the outcomes of open partial laryngectomy (OPL) versus transoral laser surgery (TLS) in patients operated on for supraglottic laryngeal carcinoma based on functional parameters (duration of hospitalization, oral nutritional status and duration of transition to oral feeding, weaning status and duration after tracheotomy, and postoperative voice results) and oncological results (overall survival rate, disease-specific survival rate, recurrence, and presence of second primary tumors) in both groups.Methods: All laryngeal carcinoma patients who had undergone either OPL or TLS in the period from January 2012 to March 2017 in our center and were followed-up at least for 36 months were included in the study. Statistical analyses were carried out using the t-test and the Mann-Whitney U test to compare the means, and the Kaplan-Meier test for survival analysis.Results: Fifty patients (44 males and 6 females) met the study criteria, of whom 31 had undergone OPL and 19 TLS. Patients that underwent TLS had less tracheotomy needs, needed shorter hospitalization periods, and transitioned to oral feeding earlier, compared to those that underwent OPL. There were no significant differences between the two groups based on oral feeding rates and voice outcomes. The impact of TLS and OPL on organ preservation in supraglottic laryngeal cancer were comparable. For local recurrences, repeated endolaryngeal laser surgeries and adjuvant treatments could be used in the TLS patient group. There were no significant differences between the two groups based on overall survival rate and disease specific survival rate.Conclusion: Although no significant differences were found in our study between the two surgical procedures in terms of oncological outcomes, TLS appeared to produce better functional outcomes in supraglottic laryngeal carcinoma than OPL. |
| first_indexed | 2024-04-10T13:38:27Z |
| format | Article |
| id | doaj.art-fc1c704ec67042fd8e199b2152f89996 |
| institution | Directory Open Access Journal |
| issn | 2667-7474 |
| language | English |
| last_indexed | 2024-04-10T13:38:27Z |
| publishDate | 2020-12-01 |
| publisher | Galenos Yayincilik |
| record_format | Article |
| series | Turkish Archives of Otorhinolaryngology |
| spelling | doaj.art-fc1c704ec67042fd8e199b2152f899962023-02-15T16:11:19ZengGalenos YayincilikTurkish Archives of Otorhinolaryngology2667-74742020-12-0158422723310.5152/tao.2020.557313049054Functional and Oncological Outcomes of Open Partial Laryngectomy vs. Transoral Laser Surgery in Supraglottic Larynx CancerMuhammet Fatih Gökmen0Zahide Çiler Büyükatalay1Süha Beton2Mustafa Kürşat Gökcan3Gürsel Dursun4Cem Meço5Tarık Babür Küçük6 Department of Otorhinolaryngology, Ankara University School of Medicine, Ankara, Turkey Department of Otorhinolaryngology, Ankara University School of Medicine, Ankara, Turkey Department of Otorhinolaryngology, Ankara University School of Medicine, Ankara, Turkey Department of Otorhinolaryngology, Ankara University School of Medicine, Ankara, Turkey Department of Otorhinolaryngology, Ankara University School of Medicine, Ankara, Turkey Department of Otorhinolaryngology, Ankara University School of Medicine, Ankara, Turkey Department of Otorhinolaryngology, Ankara University School of Medicine, Ankara, Turkey Objective: The aim of the presented study was to evaluate the outcomes of open partial laryngectomy (OPL) versus transoral laser surgery (TLS) in patients operated on for supraglottic laryngeal carcinoma based on functional parameters (duration of hospitalization, oral nutritional status and duration of transition to oral feeding, weaning status and duration after tracheotomy, and postoperative voice results) and oncological results (overall survival rate, disease-specific survival rate, recurrence, and presence of second primary tumors) in both groups.Methods: All laryngeal carcinoma patients who had undergone either OPL or TLS in the period from January 2012 to March 2017 in our center and were followed-up at least for 36 months were included in the study. Statistical analyses were carried out using the t-test and the Mann-Whitney U test to compare the means, and the Kaplan-Meier test for survival analysis.Results: Fifty patients (44 males and 6 females) met the study criteria, of whom 31 had undergone OPL and 19 TLS. Patients that underwent TLS had less tracheotomy needs, needed shorter hospitalization periods, and transitioned to oral feeding earlier, compared to those that underwent OPL. There were no significant differences between the two groups based on oral feeding rates and voice outcomes. The impact of TLS and OPL on organ preservation in supraglottic laryngeal cancer were comparable. For local recurrences, repeated endolaryngeal laser surgeries and adjuvant treatments could be used in the TLS patient group. There were no significant differences between the two groups based on overall survival rate and disease specific survival rate.Conclusion: Although no significant differences were found in our study between the two surgical procedures in terms of oncological outcomes, TLS appeared to produce better functional outcomes in supraglottic laryngeal carcinoma than OPL. http://turkarchotolaryngol.net/archives/archive-detail/article-preview/functional-and-oncological-outcomes-of-open-partia/43861 larynx cancerlaryngectomylaser therapytracheotomysurvival analysis |
| spellingShingle | Muhammet Fatih Gökmen Zahide Çiler Büyükatalay Süha Beton Mustafa Kürşat Gökcan Gürsel Dursun Cem Meço Tarık Babür Küçük Functional and Oncological Outcomes of Open Partial Laryngectomy vs. Transoral Laser Surgery in Supraglottic Larynx Cancer Turkish Archives of Otorhinolaryngology larynx cancer laryngectomy laser therapy tracheotomy survival analysis |
| title | Functional and Oncological Outcomes of Open Partial Laryngectomy vs. Transoral Laser Surgery in Supraglottic Larynx Cancer |
| title_full | Functional and Oncological Outcomes of Open Partial Laryngectomy vs. Transoral Laser Surgery in Supraglottic Larynx Cancer |
| title_fullStr | Functional and Oncological Outcomes of Open Partial Laryngectomy vs. Transoral Laser Surgery in Supraglottic Larynx Cancer |
| title_full_unstemmed | Functional and Oncological Outcomes of Open Partial Laryngectomy vs. Transoral Laser Surgery in Supraglottic Larynx Cancer |
| title_short | Functional and Oncological Outcomes of Open Partial Laryngectomy vs. Transoral Laser Surgery in Supraglottic Larynx Cancer |
| title_sort | functional and oncological outcomes of open partial laryngectomy vs transoral laser surgery in supraglottic larynx cancer |
| topic | larynx cancer laryngectomy laser therapy tracheotomy survival analysis |
| url |
http://turkarchotolaryngol.net/archives/archive-detail/article-preview/functional-and-oncological-outcomes-of-open-partia/43861
|
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