Modern Methods for the Sustainable Synthesis of Metalloporphyrins
Metalloporphyrins are involved in many and diverse applications that require the preparation of these compounds in an efficient manner, which nowadays, also involves taking into consideration sustainability issues. In this context, we use ball milling mechanochemistry and sonochemistry for the ratio...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-11-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/26/21/6652 |
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| author | Carla Gomes Mariana Peixoto Marta Pineiro |
| author_facet | Carla Gomes Mariana Peixoto Marta Pineiro |
| author_sort | Carla Gomes |
| collection | DOAJ |
| description | Metalloporphyrins are involved in many and diverse applications that require the preparation of these compounds in an efficient manner, which nowadays, also involves taking into consideration sustainability issues. In this context, we use ball milling mechanochemistry and sonochemistry for the rational development of synthetic strategies for the sustainable preparation of metalloporphyrins. Zinc, copper, cobalt and palladium complexes of hydrophobic porphyrins were obtained in high yields and under mechanical action with a moderate excess of the metal salt, without any solvent or additive. Sonochemistry prove to be a good alternative for the preparation of metal complexes of water-soluble porphyrins in good yields and short reaction times. Both strategies have good sustainability scores, close to the ideal values, which is useful in comparing and helping to choose the more adequate method. |
| first_indexed | 2024-03-10T05:56:23Z |
| format | Article |
| id | doaj.art-fc1db6dc4aea49fca62e19073b1ea3ad |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T05:56:23Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-fc1db6dc4aea49fca62e19073b1ea3ad2023-11-22T21:24:31ZengMDPI AGMolecules1420-30492021-11-012621665210.3390/molecules26216652Modern Methods for the Sustainable Synthesis of MetalloporphyrinsCarla Gomes0Mariana Peixoto1Marta Pineiro2Department of Chemistry and CQC, University of Coimbra, Rua Larga 2, 3004-535 Coimbra, PortugalDepartment of Chemistry and CQC, University of Coimbra, Rua Larga 2, 3004-535 Coimbra, PortugalDepartment of Chemistry and CQC, University of Coimbra, Rua Larga 2, 3004-535 Coimbra, PortugalMetalloporphyrins are involved in many and diverse applications that require the preparation of these compounds in an efficient manner, which nowadays, also involves taking into consideration sustainability issues. In this context, we use ball milling mechanochemistry and sonochemistry for the rational development of synthetic strategies for the sustainable preparation of metalloporphyrins. Zinc, copper, cobalt and palladium complexes of hydrophobic porphyrins were obtained in high yields and under mechanical action with a moderate excess of the metal salt, without any solvent or additive. Sonochemistry prove to be a good alternative for the preparation of metal complexes of water-soluble porphyrins in good yields and short reaction times. Both strategies have good sustainability scores, close to the ideal values, which is useful in comparing and helping to choose the more adequate method.https://www.mdpi.com/1420-3049/26/21/6652metalloporphyrinsmechanochemistryultrasoundgreen chemistryAtom EconomyE-factor |
| spellingShingle | Carla Gomes Mariana Peixoto Marta Pineiro Modern Methods for the Sustainable Synthesis of Metalloporphyrins Molecules metalloporphyrins mechanochemistry ultrasound green chemistry Atom Economy E-factor |
| title | Modern Methods for the Sustainable Synthesis of Metalloporphyrins |
| title_full | Modern Methods for the Sustainable Synthesis of Metalloporphyrins |
| title_fullStr | Modern Methods for the Sustainable Synthesis of Metalloporphyrins |
| title_full_unstemmed | Modern Methods for the Sustainable Synthesis of Metalloporphyrins |
| title_short | Modern Methods for the Sustainable Synthesis of Metalloporphyrins |
| title_sort | modern methods for the sustainable synthesis of metalloporphyrins |
| topic | metalloporphyrins mechanochemistry ultrasound green chemistry Atom Economy E-factor |
| url | https://www.mdpi.com/1420-3049/26/21/6652 |
| work_keys_str_mv | AT carlagomes modernmethodsforthesustainablesynthesisofmetalloporphyrins AT marianapeixoto modernmethodsforthesustainablesynthesisofmetalloporphyrins AT martapineiro modernmethodsforthesustainablesynthesisofmetalloporphyrins |