Effects of a brief mindfulness meditation practice on Pavlovian-to-instrumental transfer in alcohol use disorder – a pilot study
IntroductionPavlovian conditioned contextual cues have been suggested to modulate instrumental action and might explain maladaptive behavior such as relapse in participants suffering from alcohol use disorder (AUD). Pavlovian-to-Instrumental transfer (PIT) experimentally assesses the magnitude of th...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-04-01
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| Series: | Frontiers in Psychiatry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1134458/full |
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| author | Annika Rosenthal Annika Rosenthal Maria Garbusow Nina Romanczuk-Seiferth Nina Romanczuk-Seiferth Anne Beck |
| author_facet | Annika Rosenthal Annika Rosenthal Maria Garbusow Nina Romanczuk-Seiferth Nina Romanczuk-Seiferth Anne Beck |
| author_sort | Annika Rosenthal |
| collection | DOAJ |
| description | IntroductionPavlovian conditioned contextual cues have been suggested to modulate instrumental action and might explain maladaptive behavior such as relapse in participants suffering from alcohol use disorder (AUD). Pavlovian-to-Instrumental transfer (PIT) experimentally assesses the magnitude of this context-dependent effect and studies have shown a larger PIT effect in AUD populations. Taken this into account, a reduction of the influence of cues on behavior seems warranted and one approach that could alter such cue reactivity is mindfulness. Mindfulness-based interventions have been shown to be efficient in the treatment of AUD, but underlying mechanisms are yet to be elucidated. Therefore, we aim at investigating the effect of a brief mindful body scan meditation on the magnitude of the PIT effect in AUD subjects and matched controls.MethodsUsing a randomized within-subjects design, we compared the effect of a short audio guided body scan meditation against a control condition (audio of nature sounds) on PIT in healthy (n = 35) and AUD (n = 27) participants.ResultsWe found no differences in PIT effect between healthy and AUD participants as well as between conditions. However, a significant interaction effect points to a decreased PIT effect after body scan meditation in AUD subjects only.DiscussionThese pilot results suggest that AUD might be susceptible to mindfulness-induced changes in PIT, with these findings contributing to entangling the underlying mechanisms of the efficacy of mindfulness-based interventions in AUD. However, further investigation should confirm these preliminary results and the efficacy of mindfulness meditation practice in decreasing the PIT effect. |
| first_indexed | 2024-04-09T16:17:41Z |
| format | Article |
| id | doaj.art-fc21c132f14e4261ac78c95a25eb1e81 |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-04-09T16:17:41Z |
| publishDate | 2023-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-fc21c132f14e4261ac78c95a25eb1e812023-04-24T04:20:04ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402023-04-011410.3389/fpsyt.2023.11344581134458Effects of a brief mindfulness meditation practice on Pavlovian-to-instrumental transfer in alcohol use disorder – a pilot studyAnnika Rosenthal0Annika Rosenthal1Maria Garbusow2Nina Romanczuk-Seiferth3Nina Romanczuk-Seiferth4Anne Beck5Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Psychiatry and Psychotherapy, Charité – Berlin University of Medicine, Berlin, GermanyDepartment of Social and Preventive Medicine, University of Potsdam, Potsdam, GermanyCorporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Psychiatry and Psychotherapy, Charité – Berlin University of Medicine, Berlin, GermanyCorporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Psychiatry and Psychotherapy, Charité – Berlin University of Medicine, Berlin, GermanyDepartment of Psychology, Clinical Psychology and Psychotherapy, MSB Medical School Berlin, Berlin, GermanyFaculty of Health Sciences, Health and Medical University, University of Potsdam, Potsdam, GermanyIntroductionPavlovian conditioned contextual cues have been suggested to modulate instrumental action and might explain maladaptive behavior such as relapse in participants suffering from alcohol use disorder (AUD). Pavlovian-to-Instrumental transfer (PIT) experimentally assesses the magnitude of this context-dependent effect and studies have shown a larger PIT effect in AUD populations. Taken this into account, a reduction of the influence of cues on behavior seems warranted and one approach that could alter such cue reactivity is mindfulness. Mindfulness-based interventions have been shown to be efficient in the treatment of AUD, but underlying mechanisms are yet to be elucidated. Therefore, we aim at investigating the effect of a brief mindful body scan meditation on the magnitude of the PIT effect in AUD subjects and matched controls.MethodsUsing a randomized within-subjects design, we compared the effect of a short audio guided body scan meditation against a control condition (audio of nature sounds) on PIT in healthy (n = 35) and AUD (n = 27) participants.ResultsWe found no differences in PIT effect between healthy and AUD participants as well as between conditions. However, a significant interaction effect points to a decreased PIT effect after body scan meditation in AUD subjects only.DiscussionThese pilot results suggest that AUD might be susceptible to mindfulness-induced changes in PIT, with these findings contributing to entangling the underlying mechanisms of the efficacy of mindfulness-based interventions in AUD. However, further investigation should confirm these preliminary results and the efficacy of mindfulness meditation practice in decreasing the PIT effect.https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1134458/fullmindfulnessalcohol use disorder (AUD)Pavlovian-to-instrumental transfercueintervention |
| spellingShingle | Annika Rosenthal Annika Rosenthal Maria Garbusow Nina Romanczuk-Seiferth Nina Romanczuk-Seiferth Anne Beck Effects of a brief mindfulness meditation practice on Pavlovian-to-instrumental transfer in alcohol use disorder – a pilot study Frontiers in Psychiatry mindfulness alcohol use disorder (AUD) Pavlovian-to-instrumental transfer cue intervention |
| title | Effects of a brief mindfulness meditation practice on Pavlovian-to-instrumental transfer in alcohol use disorder – a pilot study |
| title_full | Effects of a brief mindfulness meditation practice on Pavlovian-to-instrumental transfer in alcohol use disorder – a pilot study |
| title_fullStr | Effects of a brief mindfulness meditation practice on Pavlovian-to-instrumental transfer in alcohol use disorder – a pilot study |
| title_full_unstemmed | Effects of a brief mindfulness meditation practice on Pavlovian-to-instrumental transfer in alcohol use disorder – a pilot study |
| title_short | Effects of a brief mindfulness meditation practice on Pavlovian-to-instrumental transfer in alcohol use disorder – a pilot study |
| title_sort | effects of a brief mindfulness meditation practice on pavlovian to instrumental transfer in alcohol use disorder a pilot study |
| topic | mindfulness alcohol use disorder (AUD) Pavlovian-to-instrumental transfer cue intervention |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1134458/full |
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