PIK3CA Is Regulated by CUX1, Promotes Cell Growth and Metastasis in Bladder Cancer via Activating Epithelial-Mesenchymal Transition

PIK3CA Is Regulated by CUX1, Promotes Cell Growth and Metastasis in Bladder Cancer via Activating Epithelial-Mesenchymal Transition

PIK3CA is a key component of phosphatidylinositol 3-kinase (PI3K) pathway that its involvement in tumorigenesis has been revealed by previous research. However, its functions and potential mechanisms in bladder cancer are still largely undiscovered. Tissue microarray (TMA) with 66 bladder cancer pat...

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Bibliographic Details
Main Authors: Zhongyu Wang, Jun Shang, Zhiqin Li, Huanhuan Li, Chufan Zhang, Kai He, Shikang Li, Wen Ju
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Oncology
Subjects:
PIK3CA
CUX1
EMT
prognosis
bladder cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.536072/full

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