Bioactive Constituents from the Twigs of Sonneratia alba
Three pentacyclic triterpenoids: lupeol [1], oleanolic acid [2], and betulinic acid [3] were isolated from the twigs of Sonneratia alba together with 2,6-dimethoxy-p-benzoquinone [4], a mixture of stigmasterol [5] and b-sitosterol [6]. Their structures were elucidated by analyses of their 1D and 2D...
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| Format: | Article |
| Language: | English |
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Walailak University
2011-12-01
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| Series: | Walailak Journal of Science and Technology |
| Subjects: | |
| Online Access: | http://wjst.wu.ac.th/index.php/wjst/article/view/196 |
| _version_ | 1818016268470452224 |
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| author | Kanchuree CHAIYADEJ Hathaichanok WONGTHAP Surasi VADHANAVIKIT Kan CHANTRAPROMMA |
| author_facet | Kanchuree CHAIYADEJ Hathaichanok WONGTHAP Surasi VADHANAVIKIT Kan CHANTRAPROMMA |
| author_sort | Kanchuree CHAIYADEJ |
| collection | DOAJ |
| description | Three pentacyclic triterpenoids: lupeol [1], oleanolic acid [2], and betulinic acid [3] were isolated from the twigs of Sonneratia alba together with 2,6-dimethoxy-p-benzoquinone [4], a mixture of stigmasterol [5] and b-sitosterol [6]. Their structures were elucidated by analyses of their 1D and 2D NMR, and their physical and spectral data were compared with those reported in the literature. Amongst these isolates, compounds [2,3] exhibit antimycobacterial activity with MIC values of 25 and 50 mg/ml respectively. In addition, compound [4] exhibited antimalarial activity against P. falciparum with an IC50 value of 3.08 mg/ml. |
| first_indexed | 2024-04-14T07:10:58Z |
| format | Article |
| id | doaj.art-fc23c41197b94ffda5333e3df8ba87f5 |
| institution | Directory Open Access Journal |
| issn | 1686-3933 2228-835X |
| language | English |
| last_indexed | 2024-04-14T07:10:58Z |
| publishDate | 2011-12-01 |
| publisher | Walailak University |
| record_format | Article |
| series | Walailak Journal of Science and Technology |
| spelling | doaj.art-fc23c41197b94ffda5333e3df8ba87f52022-12-22T02:06:27ZengWalailak UniversityWalailak Journal of Science and Technology1686-39332228-835X2011-12-011110.2004/wjst.v1i1.196189Bioactive Constituents from the Twigs of Sonneratia albaKanchuree CHAIYADEJ0Hathaichanok WONGTHAP1Surasi VADHANAVIKIT2Kan CHANTRAPROMMA3Center for Scientific and Technological Equipment, Walailak University, Thasala, Nakhon Si Thammarat 80161School of Science, Walailak University, Thasala, Nakhon Si Thammarat 80161School of Allied Health Sciences and Public Health, Walailak University, Thasala, Nakhon Si Thammarat 80161School of Science, Walailak University, Thasala, Nakhon Si Thammarat 80161Three pentacyclic triterpenoids: lupeol [1], oleanolic acid [2], and betulinic acid [3] were isolated from the twigs of Sonneratia alba together with 2,6-dimethoxy-p-benzoquinone [4], a mixture of stigmasterol [5] and b-sitosterol [6]. Their structures were elucidated by analyses of their 1D and 2D NMR, and their physical and spectral data were compared with those reported in the literature. Amongst these isolates, compounds [2,3] exhibit antimycobacterial activity with MIC values of 25 and 50 mg/ml respectively. In addition, compound [4] exhibited antimalarial activity against P. falciparum with an IC50 value of 3.08 mg/ml.http://wjst.wu.ac.th/index.php/wjst/article/view/196Sonneratia albaSonneraceaeTriterpenoidsQuinoneAntimalarialAntimycobacterial |
| spellingShingle | Kanchuree CHAIYADEJ Hathaichanok WONGTHAP Surasi VADHANAVIKIT Kan CHANTRAPROMMA Bioactive Constituents from the Twigs of Sonneratia alba Walailak Journal of Science and Technology Sonneratia alba Sonneraceae Triterpenoids Quinone Antimalarial Antimycobacterial |
| title | Bioactive Constituents from the Twigs of Sonneratia alba |
| title_full | Bioactive Constituents from the Twigs of Sonneratia alba |
| title_fullStr | Bioactive Constituents from the Twigs of Sonneratia alba |
| title_full_unstemmed | Bioactive Constituents from the Twigs of Sonneratia alba |
| title_short | Bioactive Constituents from the Twigs of Sonneratia alba |
| title_sort | bioactive constituents from the twigs of sonneratia alba |
| topic | Sonneratia alba Sonneraceae Triterpenoids Quinone Antimalarial Antimycobacterial |
| url | http://wjst.wu.ac.th/index.php/wjst/article/view/196 |
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