Activating Transcription Factor 4 (ATF4) Modulates Post-synaptic Development and Dendritic Spine Morphology

Activating Transcription Factor 4 (ATF4) Modulates Post-synaptic Development and Dendritic Spine Morphology

The ubiquitously expressed activating transcription factor 4 (ATF4) has been variably reported to either promote or inhibit neuronal plasticity and memory. However, the potential cellular bases for these and other actions of ATF4 in brain are not well defined. In this report, we focus on ATF4’s role...

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Bibliographic Details
Main Authors: Jin eLiu, Silvia ePasini, Michael L Shelanski, Lloyd A Greene
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Cdc42
filopodia
ATF4
mushroom spine
post-synaptic development
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00177/full

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