A case report of preferential effectiveness of clonazepam over lorazepam in the management of a case of alprazolam withdrawal
Benzodiazepines (BZDs) remain the mainstay in the management of withdrawal arising out of BZD use disorders. The choice of detoxifying agent is determined by the duration of action and also by the metabolic properties of the drug. Very rarely, we consider the chemical properties of the drug that we...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2018-01-01
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| Series: | Journal of Geriatric Mental Health |
| Subjects: | |
| Online Access: | http://www.jgmh.org/article.asp?issn=2348-9995;year=2018;volume=5;issue=2;spage=165;epage=166;aulast=Saxena |
| _version_ | 1811304578848653312 |
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| author | Vrinda Saxena Robin Victor Arghya Pal |
| author_facet | Vrinda Saxena Robin Victor Arghya Pal |
| author_sort | Vrinda Saxena |
| collection | DOAJ |
| description | Benzodiazepines (BZDs) remain the mainstay in the management of withdrawal arising out of BZD use disorders. The choice of detoxifying agent is determined by the duration of action and also by the metabolic properties of the drug. Very rarely, we consider the chemical properties of the drug that we choose, though occasionally that may have profound clinical impact on the outcome. In this case report, we present the case of alprazolam withdrawal that was ineffectively managed by lorazepam and finally salvaged by the use of clonazepam. The chemical properties of the molecules involved and their clinical importance in the decision-making process have been subsequently reviewed. |
| first_indexed | 2024-04-13T08:08:41Z |
| format | Article |
| id | doaj.art-fc244ad71e734258ad63e4bf11fbfefc |
| institution | Directory Open Access Journal |
| issn | 2348-9995 2395-3322 |
| language | English |
| last_indexed | 2024-04-13T08:08:41Z |
| publishDate | 2018-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Geriatric Mental Health |
| spelling | doaj.art-fc244ad71e734258ad63e4bf11fbfefc2022-12-22T02:55:04ZengWolters Kluwer Medknow PublicationsJournal of Geriatric Mental Health2348-99952395-33222018-01-015216516610.4103/jgmh.jgmh_25_18A case report of preferential effectiveness of clonazepam over lorazepam in the management of a case of alprazolam withdrawalVrinda SaxenaRobin VictorArghya PalBenzodiazepines (BZDs) remain the mainstay in the management of withdrawal arising out of BZD use disorders. The choice of detoxifying agent is determined by the duration of action and also by the metabolic properties of the drug. Very rarely, we consider the chemical properties of the drug that we choose, though occasionally that may have profound clinical impact on the outcome. In this case report, we present the case of alprazolam withdrawal that was ineffectively managed by lorazepam and finally salvaged by the use of clonazepam. The chemical properties of the molecules involved and their clinical importance in the decision-making process have been subsequently reviewed.http://www.jgmh.org/article.asp?issn=2348-9995;year=2018;volume=5;issue=2;spage=165;epage=166;aulast=SaxenaAlprazolamclonazepamlorazepamwithdrawal |
| spellingShingle | Vrinda Saxena Robin Victor Arghya Pal A case report of preferential effectiveness of clonazepam over lorazepam in the management of a case of alprazolam withdrawal Journal of Geriatric Mental Health Alprazolam clonazepam lorazepam withdrawal |
| title | A case report of preferential effectiveness of clonazepam over lorazepam in the management of a case of alprazolam withdrawal |
| title_full | A case report of preferential effectiveness of clonazepam over lorazepam in the management of a case of alprazolam withdrawal |
| title_fullStr | A case report of preferential effectiveness of clonazepam over lorazepam in the management of a case of alprazolam withdrawal |
| title_full_unstemmed | A case report of preferential effectiveness of clonazepam over lorazepam in the management of a case of alprazolam withdrawal |
| title_short | A case report of preferential effectiveness of clonazepam over lorazepam in the management of a case of alprazolam withdrawal |
| title_sort | case report of preferential effectiveness of clonazepam over lorazepam in the management of a case of alprazolam withdrawal |
| topic | Alprazolam clonazepam lorazepam withdrawal |
| url | http://www.jgmh.org/article.asp?issn=2348-9995;year=2018;volume=5;issue=2;spage=165;epage=166;aulast=Saxena |
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