DRESS syndrome induced by anticonvulsants and fulminant hepatic failure

The drug rash with eosinophilia and systemic symptoms syndrome (DRESS) is a severe hypersensitive reaction induced by the use of medications. More than 100 drugs associated with this syndrome have been reported and, although most patients have a favorable clinical course, about 10% develop multiple...

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Bibliographic Details
Main Authors: Hector Fabio Londoño-Arcila, María Alejandra Guerra-Pabón, Cristhian David Hernández-Revelo, Diego Fernando Hoyos-Samboní, Katherine Vanessa Jiménez-Orrego
Format: Article
Language:English
Published: Universidad Nacional de Colombia 2017-01-01
Series:Revista de la Facultad de Medicina
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Online Access:https://revistas.unal.edu.co/index.php/revfacmed/article/view/51919
Description
Summary:The drug rash with eosinophilia and systemic symptoms syndrome (DRESS) is a severe hypersensitive reaction induced by the use of medications. More than 100 drugs associated with this syndrome have been reported and, although most patients have a favorable clinical course, about 10% develop multiple organ failure; some cases may result in the death of the patient. This paper presents a clinical case of DRESS syndrome associated with anticonvulsive therapy that evolved to fulminant hepatic failure. The etiology, pathogenesis, clinical manifestations, diagnostic process and possible treatment of this condition are addressed.
ISSN:0120-0011
2357-3848