CAR links hypoxia signaling to improved survival after myocardial infarction

CAR links hypoxia signaling to improved survival after myocardial infarction

Heart attack: Inhibiting cell contact protein may limit damage During a heart attack the death of heart muscle cells causes lesions that transform into fibrotic tissue. Restricting the damage is critical, as mamalian heart muslce does not regenerate. The cell contact protein CAR, is upregulated in t...

Full description

Bibliographic Details
Main Authors:	Fabian Freiberg, Meghna Thakkar, Wiebke Hamann, Jacobo Lopez Carballo, Rene Jüttner, Felizia K. Voss, Peter M. Becher, Dirk Westermann, Carsten Tschöpe, Arnd Heuser, Oliver Rocks, Robert Fischer, Michael Gotthardt
Format:	Article
Language:	English
Published:	Nature Publishing Group 2023-03-01
Series:	Experimental and Molecular Medicine
Online Access:	https://doi.org/10.1038/s12276-023-00963-9

Similar Items

The IgCAM CAR Regulates Gap Junction-Mediated Coupling on Embryonic Cardiomyocytes and Affects Their Beating Frequency
by: Claudia Matthaeus, et al.
Published: (2022-12-01)

How to perform an endomyocardial biopsy?
by: Carsten Tschöpe, et al.
Published: (2015-09-01)

Hypoxia Selectively Impairs CAR-T Cells In Vitro
by: Robert Berahovich, et al.
Published: (2019-04-01)

Treatment of Transthyretin Amyloid Cardiomyopathy: The Current Options, the Future, and the Challenges
by: Carsten Tschöpe, et al.
Published: (2022-04-01)

Progress in construction of hypoxia-sensitive CAR-T cell for solid tumor therapy
by: XUE Ying, MAO Yunyu, XU Jianqing
Published: (2023-01-01)

The IgSF Cell Adhesion Protein CLMP and Congenital Short Bowel Syndrome (CSBS)
by: Fritz G. Rathjen, et al.
Published: (2023-03-01)

The immunoproteasome‐specific inhibitor ONX 0914 reverses susceptibility to acute viral myocarditis
by: Nadine Althof, et al.
Published: (2018-02-01)

Multiplex Cytokine Analysis of Aqueous Humor in Juvenile Idiopathic Arthritis-Associated Anterior Uveitis With or Without Secondary Glaucoma
by: Dirk Bauer, et al.
Published: (2018-04-01)

RELEVANSI FINANCIAL SUSTAINABILITY MEASURES TERHADAP MANAJEMEN LABA: STUDI EMPIRIS PADA PERUSAHAAN SEKTOR PRIMER DAN SEKUNDER YANG TERDAFTAR DI BEI PERIODE 2017-2019
by: Vivian Witjaksono, et al.
Published: (2022-09-01)

Hypoxia and Microvascular Alterations Are Early Predictors of IDH-Mutated Anaplastic Glioma Recurrence
by: Andreas Stadlbauer, et al.
Published: (2021-04-01)

OIL DISPLACEMENT IN MISCIBLE CONDITION
by: Ivanka Juttner
Published: (1997-12-01)

Hypoxia-regulated secretion of IL-12 enhances antitumor activity and safety of CD19 CAR-T cells in the treatment of DLBCL
by: Wenping Zhou, et al.
Published: (2023-09-01)

On the use of smart hybrid contracts to provide flexibility in algorithmic governance
by: Carlos Molina-Jimenez, et al.
Published: (2024-01-01)

Hypoxia and hypoxia-inducible factors in leukaemias
by: Margaux eDeynoux, et al.
Published: (2016-02-01)

Cars, cars and more cars [kasetvideo]
Published: ([197)

Analysis of Traumatic Brain Injuries Sustained by Occupants in Japanese Brand Car Crashes in the US
by: Jacobo Antona-Makoshi, et al.
Published: (2018-07-01)

Hypoxia
by: P. F. Litvitsky
Published: (2016-02-01)

Hypoxia, Hypoxia-Inducible Factors and Liver Fibrosis
by: Beatrice Foglia, et al.
Published: (2021-07-01)

Epithelial coxsackievirus adenovirus receptor promotes house dust mite-induced lung inflammation
by: Elena Ortiz-Zapater, et al.
Published: (2022-10-01)

PENGARUH FEMALE EXECUTIVE TERHADAP KUALITAS LAPORAN KEUANGAN PADA SEKTOR MANUFAKTURYANG TERDAFTAR DI BEI PERIODE 2012-2014
by: Arief Kusumo Atmojo Sugiharto, et al.
Published: (2017-09-01)

Ritmo de crecimiento y longevidad de follaje del estrato arbustivo en la Reserva Biológica A. Brenes, Costa Rica
by: Elke Freiberg, et al.
Published: (1999-09-01)

Spectroscopic Characterization of Diazophosphane—A Candidate for Astrophysical Observations
by: Martin Tschöpe, et al.
Published: (2023-01-01)

Coxsackievirus-adenovirus receptor (CAR) is essential for early embryonic cardiac development.
by: Dorner, A, et al.
Published: (2005)

Dihydroartemisinin is a hypoxia-active anticancer drug in colorectal carcinoma cells
by: Teona eOntikatze, et al.
Published: (2014-05-01)

Exploration of Analgesia with Tramadol in the Coxsackievirus B3 Myocarditis Mouse Model
by: Sandra Pinkert, et al.
Published: (2021-06-01)

Hypoxia and oxidative stress in breast cancer. Hypoxia and tumourigenesis
by: Knowles, H, et al.
Published: (2001)

Hypoxia and oxidative stress in breast cancer. Hypoxia and tumourigenesis.
by: Knowles, H, et al.
Published: (2001)

DCE-MRI of Tumor Hypoxia and Hypoxia-Associated Aggressiveness
by: Jon-Vidar Gaustad, et al.
Published: (2020-07-01)

Hypoxia and Hypoxia-Inducible Factors in Kidney Injury and Repair
by: Shaoqun Shu, et al.
Published: (2019-02-01)

Hypoxia induces polycystin-1 expression in the renal epithelium
by: Steffen Grampp, et al.
Published: (2023-05-01)

Nuts! : Southwest Airlines' crazy recipe for business and personal success /
by: 239889 Freiberg, Kevin, et al.
Published: (1996)

Hypoxia and exercise /
by: Roach, Robert C., et al.
Published: (2006)

Crosstalk Between Autophagy and Hypoxia-Inducible Factor-1α in Antifungal Immunity
by: Tim Quäschling, et al.
Published: (2020-09-01)

Hypobaric hypoxia causes body weight reduction in obese subjects.
by: Lippl, F, et al.
Published: (2010)

Activation-inducible CAR expression enables precise control over engineered CAR T cell function
by: Simon P. Fraessle, et al.
Published: (2023-06-01)

Hypoxia and oxidative stress in breast cancer. Hypoxia signalling pathways.
by: Pugh, C, et al.
Published: (2001)

Tumor hypoxia and role of hypoxia-inducible factor in oral cancer
by: Pooja Singh, et al.
Published: (2024-01-01)

Elucidation of molecular mechanisms under hypoxia and hypoxia / reoxygenation conditions.
by: Chhiti Pandey.
Published: (2011)

ONX 0914 Lacks Selectivity for the Cardiac Immunoproteasome in CoxsackievirusB3 Myocarditis of NMRI Mice and Promotes Virus-Mediated Tissue Damage
by: Hannah Louise Neumaier, et al.
Published: (2020-04-01)

International comparisons of cars and car useage/
by: 400835 Tanner, J. C., et al.
Published: (1983)