Hypertriglyceridemia may contribute to stroke and pancreatitis: A case report and review of the literature
Hypertriglyceridemia (HTG) is one of the most common clinical dyslipidemia. Nevertheless, stroke and acute pancreatitis co-occurrence due to hypertriglyceridemia are extremely rare. We present a case of hypertriglyceridemia-associated stroke and pancreatitis in a 39-year-old woman. The patient’s lab...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-12-01
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| Series: | Frontiers in Endocrinology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2022.960343/full |
| _version_ | 1811213669552357376 |
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| author | Mingyu Zhang Taoyuan Yin Feng Xia Suhong Xia Wangdong Zhou Yu Zhang Xu Han Kai Zhao Lina Feng Ruonan Dong Dean Tian Yan Yu Jiazhi Liao |
| author_facet | Mingyu Zhang Taoyuan Yin Feng Xia Suhong Xia Wangdong Zhou Yu Zhang Xu Han Kai Zhao Lina Feng Ruonan Dong Dean Tian Yan Yu Jiazhi Liao |
| author_sort | Mingyu Zhang |
| collection | DOAJ |
| description | Hypertriglyceridemia (HTG) is one of the most common clinical dyslipidemia. Nevertheless, stroke and acute pancreatitis co-occurrence due to hypertriglyceridemia are extremely rare. We present a case of hypertriglyceridemia-associated stroke and pancreatitis in a 39-year-old woman. The patient’s laboratory tests reported high triglyceride concentrations beyond the instrument’s detection range, and radiological examination showed typical signs of cerebral infarction and acute pancreatitis. The patient received combined blood purification therapy, intravenous thrombolysis with urokinase, and conservative treatment of pancreatitis. We discuss the clinical features, pathogenesis, diagnosis, and treatment of hypertriglyceridemic stroke and pancreatitis combined with the relevant literature. We reviewed the mechanisms by which triglycerides contribute to atherosclerosis and acute pancreatitis. We point out the superiority of combined blood purification therapy and caution physicians about the effects of prescribed drugs on blood lipids. |
| first_indexed | 2024-04-12T05:50:11Z |
| format | Article |
| id | doaj.art-fc265876ee5447279a8bbc3a7019bb7e |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-04-12T05:50:11Z |
| publishDate | 2022-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-fc265876ee5447279a8bbc3a7019bb7e2022-12-22T03:45:20ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922022-12-011310.3389/fendo.2022.960343960343Hypertriglyceridemia may contribute to stroke and pancreatitis: A case report and review of the literatureMingyu Zhang0Taoyuan Yin1Feng Xia2Suhong Xia3Wangdong Zhou4Yu Zhang5Xu Han6Kai Zhao7Lina Feng8Ruonan Dong9Dean Tian10Yan Yu11Jiazhi Liao12Department of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, ChinaDepartment of Biliary-Pancreatic Surgery, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, ChinaDepartment of Hepatic Surgery Center, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, ChinaDepartment of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, ChinaDepartment of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, ChinaDepartment of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, ChinaDepartment of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, ChinaDepartment of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, ChinaDepartment of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, ChinaDepartment of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, ChinaDepartment of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, ChinaDepartment of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, ChinaDepartment of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, ChinaHypertriglyceridemia (HTG) is one of the most common clinical dyslipidemia. Nevertheless, stroke and acute pancreatitis co-occurrence due to hypertriglyceridemia are extremely rare. We present a case of hypertriglyceridemia-associated stroke and pancreatitis in a 39-year-old woman. The patient’s laboratory tests reported high triglyceride concentrations beyond the instrument’s detection range, and radiological examination showed typical signs of cerebral infarction and acute pancreatitis. The patient received combined blood purification therapy, intravenous thrombolysis with urokinase, and conservative treatment of pancreatitis. We discuss the clinical features, pathogenesis, diagnosis, and treatment of hypertriglyceridemic stroke and pancreatitis combined with the relevant literature. We reviewed the mechanisms by which triglycerides contribute to atherosclerosis and acute pancreatitis. We point out the superiority of combined blood purification therapy and caution physicians about the effects of prescribed drugs on blood lipids.https://www.frontiersin.org/articles/10.3389/fendo.2022.960343/fullhypertriglyceridemiastrokepancreatitismetabolic disordersblood purification |
| spellingShingle | Mingyu Zhang Taoyuan Yin Feng Xia Suhong Xia Wangdong Zhou Yu Zhang Xu Han Kai Zhao Lina Feng Ruonan Dong Dean Tian Yan Yu Jiazhi Liao Hypertriglyceridemia may contribute to stroke and pancreatitis: A case report and review of the literature Frontiers in Endocrinology hypertriglyceridemia stroke pancreatitis metabolic disorders blood purification |
| title | Hypertriglyceridemia may contribute to stroke and pancreatitis: A case report and review of the literature |
| title_full | Hypertriglyceridemia may contribute to stroke and pancreatitis: A case report and review of the literature |
| title_fullStr | Hypertriglyceridemia may contribute to stroke and pancreatitis: A case report and review of the literature |
| title_full_unstemmed | Hypertriglyceridemia may contribute to stroke and pancreatitis: A case report and review of the literature |
| title_short | Hypertriglyceridemia may contribute to stroke and pancreatitis: A case report and review of the literature |
| title_sort | hypertriglyceridemia may contribute to stroke and pancreatitis a case report and review of the literature |
| topic | hypertriglyceridemia stroke pancreatitis metabolic disorders blood purification |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2022.960343/full |
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