Familial inheritance of TMD: a case report

The TMJ is a joint that can perform both hinge and sliding motions and whose proper functioning depends on the actions of the joint and joint capsule, the muscles of mastication, and the condition and action of the mandibular condyle. If any of these components deviate from their normal structure or...

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Main Author: Maria Genello
Format: Article
Language:English
Published: University Library System, University of Pittsburgh 2017-06-01
Series:Dentistry 3000
Subjects:
Online Access:http://dentistry3000.pitt.edu/ojs/index.php/dentistry3000/article/view/75
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author Maria Genello
author_facet Maria Genello
author_sort Maria Genello
collection DOAJ
description The TMJ is a joint that can perform both hinge and sliding motions and whose proper functioning depends on the actions of the joint and joint capsule, the muscles of mastication, and the condition and action of the mandibular condyle. If any of these components deviate from their normal structure or function, then TMD can result. There have been many reported contributing factors to TMD development, many of which include environmental influences such as bruxism, trauma, and other oral habits. However, a genetic component can also play a role. This paper reports a case of TMD occurring within three consecutive generations of a family and explores the possibility of this disorder exhibiting familial inheritance. Members of the family affected all displayed manifestations of joint laxity in other areas of the body, migraines, pain, and had smaller craniofacial dimensions with a narrower mandible. These factors were found to have a genetic influence and these genes can also be tied to TMD, thus supporting the argument that the cases of TMD seen in this family are in fact due to inheritance. If TMD can be shown to have a genetic component and be inherited, then dental practitioners would be able to identify high risk patients and help to modify environmental factors early on in order to help prevent the onset of TMD in those individuals.
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spelling doaj.art-fc27e812fac848ccb234dabc62f842ca2022-12-21T20:11:29ZengUniversity Library System, University of PittsburghDentistry 30002167-86772017-06-0151656910.5195/d3000.2017.7546Familial inheritance of TMD: a case reportMaria Genello0University of Pittsburgh, School of Dental MedicineThe TMJ is a joint that can perform both hinge and sliding motions and whose proper functioning depends on the actions of the joint and joint capsule, the muscles of mastication, and the condition and action of the mandibular condyle. If any of these components deviate from their normal structure or function, then TMD can result. There have been many reported contributing factors to TMD development, many of which include environmental influences such as bruxism, trauma, and other oral habits. However, a genetic component can also play a role. This paper reports a case of TMD occurring within three consecutive generations of a family and explores the possibility of this disorder exhibiting familial inheritance. Members of the family affected all displayed manifestations of joint laxity in other areas of the body, migraines, pain, and had smaller craniofacial dimensions with a narrower mandible. These factors were found to have a genetic influence and these genes can also be tied to TMD, thus supporting the argument that the cases of TMD seen in this family are in fact due to inheritance. If TMD can be shown to have a genetic component and be inherited, then dental practitioners would be able to identify high risk patients and help to modify environmental factors early on in order to help prevent the onset of TMD in those individuals.http://dentistry3000.pitt.edu/ojs/index.php/dentistry3000/article/view/75Familial TMDsystemic joint laxitychronic headaches/paincraniofacial dimensionsTMD inheritance
spellingShingle Maria Genello
Familial inheritance of TMD: a case report
Dentistry 3000
Familial TMD
systemic joint laxity
chronic headaches/pain
craniofacial dimensions
TMD inheritance
title Familial inheritance of TMD: a case report
title_full Familial inheritance of TMD: a case report
title_fullStr Familial inheritance of TMD: a case report
title_full_unstemmed Familial inheritance of TMD: a case report
title_short Familial inheritance of TMD: a case report
title_sort familial inheritance of tmd a case report
topic Familial TMD
systemic joint laxity
chronic headaches/pain
craniofacial dimensions
TMD inheritance
url http://dentistry3000.pitt.edu/ojs/index.php/dentistry3000/article/view/75
work_keys_str_mv AT mariagenello familialinheritanceoftmdacasereport