Enhanced Dissolution and Oral Bioavailability of Piroxicam Formulations: Modulating Effect of Phospholipids

Enhanced Dissolution and Oral Bioavailability of Piroxicam Formulations: Modulating Effect of Phospholipids

Several biologically relevant phospholipids were assessed as potential carriers/additives for rapidly dissolving solid formulations of piroxicam (Biopharmaceutics Classification System Class II drug). On the basis of in vitro dissolution studies, dimyristoylphosphatidylglycerol (DMPG) was ranked as...

Full description

Bibliographic Details
Main Authors: Muhammad D. Hussain, Inna Miroshnyk, James F. Brausch, Muhammad J. Habib, Sabiruddin Mirza
Format: Article
Language:English
Published: MDPI AG 2010-10-01
Series:Pharmaceutics
Subjects:
poorly water soluble drugs
phospholipids
solid dispersions
dissolution
bioavailability
Online Access:http://www.mdpi.com/1999-4923/2/4/339/

Similar Items

Similar Items