Umbilical cord prolapse after preterm premature rupture of membranes
Objective: To investigate the incidence of umbilical cord prolapse (UCP) and its influence on infant prognosis in pregnant women with preterm premature rupture of membranes (PPROM). Materials and methods: We conducted a retrospective cohort study in a single tertiary perinatal center between 2009 an...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-05-01
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| Series: | Taiwanese Journal of Obstetrics & Gynecology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1028455922000845 |
| _version_ | 1817991393279213568 |
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| author | Kentaro Nakanishi Ryo Yamamoto Yousuke Imanishi Shusaku Hayashi Kazuko Wada Keisuke Ishii |
| author_facet | Kentaro Nakanishi Ryo Yamamoto Yousuke Imanishi Shusaku Hayashi Kazuko Wada Keisuke Ishii |
| author_sort | Kentaro Nakanishi |
| collection | DOAJ |
| description | Objective: To investigate the incidence of umbilical cord prolapse (UCP) and its influence on infant prognosis in pregnant women with preterm premature rupture of membranes (PPROM). Materials and methods: We conducted a retrospective cohort study in a single tertiary perinatal center between 2009 and 2017. Singleton pregnancies with PPROM that occurred between 22 and 33 weeks of gestation were included. Infantile composite adverse outcome consisted of death, severe intraventricular hemorrhage, cystic periventricular leukomalacia, necrotizing enterocolitis, and sepsis before discharge. Infantile outcomes were compared between pregnancies that were complicated by UCP and those that were not. Results: Out of 208 singleton pregnancies included in the analysis, UCP occurred in 12 (5.8%) cases. The gestational age of pregnancies with UCP was significantly lesser than that of those without UCP. The incidence of infantile composite adverse outcome in patients with UCP was 16.7%, and this was not significantly higher than the incidence in patients without UCP (6.6%, P = 0.21). UCP was not shown to be associated with infantile composite adverse outcome in a multivariate regression model. Gestational age <25 weeks at delivery was significantly associated with infantile composite adverse outcome. Conclusions: The incidence of UCP was 5.8% among singleton pregnancies, with PPROM being managed expectantly between 22 and 33 weeks’ gestation. Preterm UCP may not be associated with infantile adverse outcomes provided emergency cesarean delivery is available at all time. |
| first_indexed | 2024-04-14T01:11:45Z |
| format | Article |
| id | doaj.art-fc2a742d803c43e5bb6f3662e9cf1f0b |
| institution | Directory Open Access Journal |
| issn | 1028-4559 |
| language | English |
| last_indexed | 2024-04-14T01:11:45Z |
| publishDate | 2022-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Taiwanese Journal of Obstetrics & Gynecology |
| spelling | doaj.art-fc2a742d803c43e5bb6f3662e9cf1f0b2022-12-22T02:21:01ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592022-05-01613489493Umbilical cord prolapse after preterm premature rupture of membranesKentaro Nakanishi0Ryo Yamamoto1Yousuke Imanishi2Shusaku Hayashi3Kazuko Wada4Keisuke Ishii5Department of Maternal Fetal Medicine, Osaka Women's and Children's Hospital, Osaka, JapanDepartment of Maternal Fetal Medicine, Osaka Women's and Children's Hospital, Osaka, Japan; Corresponding author. 840, Murodo-cho, Izumi, Osaka, 5941101, Japan. Fax: +81 725-56-5682.Department of Neonatology, Osaka Women's and Children's Hospital, Osaka, JapanDepartment of Maternal Fetal Medicine, Osaka Women's and Children's Hospital, Osaka, JapanDepartment of Neonatology, Osaka Women's and Children's Hospital, Osaka, JapanDepartment of Maternal Fetal Medicine, Osaka Women's and Children's Hospital, Osaka, JapanObjective: To investigate the incidence of umbilical cord prolapse (UCP) and its influence on infant prognosis in pregnant women with preterm premature rupture of membranes (PPROM). Materials and methods: We conducted a retrospective cohort study in a single tertiary perinatal center between 2009 and 2017. Singleton pregnancies with PPROM that occurred between 22 and 33 weeks of gestation were included. Infantile composite adverse outcome consisted of death, severe intraventricular hemorrhage, cystic periventricular leukomalacia, necrotizing enterocolitis, and sepsis before discharge. Infantile outcomes were compared between pregnancies that were complicated by UCP and those that were not. Results: Out of 208 singleton pregnancies included in the analysis, UCP occurred in 12 (5.8%) cases. The gestational age of pregnancies with UCP was significantly lesser than that of those without UCP. The incidence of infantile composite adverse outcome in patients with UCP was 16.7%, and this was not significantly higher than the incidence in patients without UCP (6.6%, P = 0.21). UCP was not shown to be associated with infantile composite adverse outcome in a multivariate regression model. Gestational age <25 weeks at delivery was significantly associated with infantile composite adverse outcome. Conclusions: The incidence of UCP was 5.8% among singleton pregnancies, with PPROM being managed expectantly between 22 and 33 weeks’ gestation. Preterm UCP may not be associated with infantile adverse outcomes provided emergency cesarean delivery is available at all time.http://www.sciencedirect.com/science/article/pii/S1028455922000845Umbilical cord prolapsePreterm premature rupture of membranesObstetric complicationsEmergency deliveryInfantile adverse outcome |
| spellingShingle | Kentaro Nakanishi Ryo Yamamoto Yousuke Imanishi Shusaku Hayashi Kazuko Wada Keisuke Ishii Umbilical cord prolapse after preterm premature rupture of membranes Taiwanese Journal of Obstetrics & Gynecology Umbilical cord prolapse Preterm premature rupture of membranes Obstetric complications Emergency delivery Infantile adverse outcome |
| title | Umbilical cord prolapse after preterm premature rupture of membranes |
| title_full | Umbilical cord prolapse after preterm premature rupture of membranes |
| title_fullStr | Umbilical cord prolapse after preterm premature rupture of membranes |
| title_full_unstemmed | Umbilical cord prolapse after preterm premature rupture of membranes |
| title_short | Umbilical cord prolapse after preterm premature rupture of membranes |
| title_sort | umbilical cord prolapse after preterm premature rupture of membranes |
| topic | Umbilical cord prolapse Preterm premature rupture of membranes Obstetric complications Emergency delivery Infantile adverse outcome |
| url | http://www.sciencedirect.com/science/article/pii/S1028455922000845 |
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