A pilot study of alternative substrates in the critically Ill subject using a ketogenic feed

A pilot study of alternative substrates in the critically Ill subject using a ketogenic feed

Abstract Bioenergetic failure caused by impaired utilisation of glucose and fatty acids contributes to organ dysfunction across multiple tissues in critical illness. Ketone bodies may form an alternative substrate source, but the feasibility and safety of inducing a ketogenic state in physiologicall...

Full description

Bibliographic Details
Main Authors: Angela McNelly, Anne Langan, Danielle E. Bear, Alexandria Page, Tim Martin, Fatima Seidu, Filipa Santos, Kieron Rooney, Kaifeng Liang, Simon J. Heales, Tomas Baldwin, Isabelle Alldritt, Hannah Crossland, Philip J. Atherton, Daniel Wilkinson, Hugh Montgomery, John Prowle, Rupert Pearse, Simon Eaton, Zudin A. Puthucheary
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-42659-8

Internet

https://doi.org/10.1038/s41467-023-42659-8

Similar Items