Aneuploidy and DNA Methylation as Mirrored Features of Early Human Embryo Development

Aneuploidy and DNA Methylation as Mirrored Features of Early Human Embryo Development

Genome stability is an integral feature of all living organisms. Aneuploidy is the most common cause of fetal death in humans. The timing of bursts in increased aneuploidy frequency coincides with the waves of global epigenetic reprogramming in mammals. During gametogenesis and early embryogenesis,...

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Bibliographic Details
Main Authors: Ekaterina N. Tolmacheva, Stanislav A. Vasilyev, Igor N. Lebedev
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Genes
Subjects:
aneuploidy
DNA methylation
human embryogenesis
epigenetic reprogramming
Online Access:https://www.mdpi.com/2073-4425/11/9/1084

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