Tidal volumes during delivery room stabilization of (near) term infants
Abstract Background We sought to assess tidal volumes in (near) term infants during delivery room stabilization. Methods Secondary analysis of a prospective study comparing two facemasks used for positive pressure ventilation (PPV) in newborn infants ≥ 34 weeks gestation. PPV was provided with a T-p...
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| Format: | Article |
| Language: | English |
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BMC
2022-09-01
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| Series: | BMC Pediatrics |
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| Online Access: | https://doi.org/10.1186/s12887-022-03600-y |
| _version_ | 1811267351043112960 |
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| author | Janine Thomann Christoph M. Rüegger Vincent D. Gaertner Eoin O’Currain Omar F. Kamlin Peter G. Davis Laila Springer |
| author_facet | Janine Thomann Christoph M. Rüegger Vincent D. Gaertner Eoin O’Currain Omar F. Kamlin Peter G. Davis Laila Springer |
| author_sort | Janine Thomann |
| collection | DOAJ |
| description | Abstract Background We sought to assess tidal volumes in (near) term infants during delivery room stabilization. Methods Secondary analysis of a prospective study comparing two facemasks used for positive pressure ventilation (PPV) in newborn infants ≥ 34 weeks gestation. PPV was provided with a T-piece device with a PIP of 30 cmH2O and positive end-expiratory airway pressure of 5 cmH2O. Expired tidal volumes (Vt) were measured with a respiratory function monitor. Target range for Vt was defined to be 4 – 8 ml/kg. Results Twenty-three infants with a median (IQR) gestational age of 38.1 (36.4 – 39.0) weeks received 1828 inflations with a median Vt of 4.6 (3.3 – 6.2) ml/kg. Median Vt was in the target range in 12 infants (52%), lower in 9 (39%) and higher in 2 (9%). Thirty-six (25—27) % of the inflations were in the target rage over the duration of PPV while 42 (25 – 65) % and 10 (3 – 33) % were above and below target range. Conclusions Variability of expiratory tidal volume delivered to term and late preterm infants was wide. Reliance on standard pressures and clinical signs may be insufficient to provide safe and effective ventilation in the delivery room. Trial registration This is a secondary analysis of a prospectively registered randomized controlled trial (ACTRN12616000768493). |
| first_indexed | 2024-04-12T21:00:55Z |
| format | Article |
| id | doaj.art-fc3697312420445888a090c95a8fb417 |
| institution | Directory Open Access Journal |
| issn | 1471-2431 |
| language | English |
| last_indexed | 2024-04-12T21:00:55Z |
| publishDate | 2022-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pediatrics |
| spelling | doaj.art-fc3697312420445888a090c95a8fb4172022-12-22T03:16:51ZengBMCBMC Pediatrics1471-24312022-09-012211610.1186/s12887-022-03600-yTidal volumes during delivery room stabilization of (near) term infantsJanine Thomann0Christoph M. Rüegger1Vincent D. Gaertner2Eoin O’Currain3Omar F. Kamlin4Peter G. Davis5Laila Springer6Department of Neonatology, Newborn Research, University Hospital and University of ZurichDepartment of Neonatology, Newborn Research, University Hospital and University of ZurichDepartment of Neonatology, Newborn Research, University Hospital and University of ZurichSchool of Medicine, University College Dublin and National Maternity Hospital DublinNewborn Research Centre and Neonatal Services, The Royal Women’s HospitalNewborn Research Centre and Neonatal Services, The Royal Women’s HospitalDepartment of Neonatology, University Clinic TübingenAbstract Background We sought to assess tidal volumes in (near) term infants during delivery room stabilization. Methods Secondary analysis of a prospective study comparing two facemasks used for positive pressure ventilation (PPV) in newborn infants ≥ 34 weeks gestation. PPV was provided with a T-piece device with a PIP of 30 cmH2O and positive end-expiratory airway pressure of 5 cmH2O. Expired tidal volumes (Vt) were measured with a respiratory function monitor. Target range for Vt was defined to be 4 – 8 ml/kg. Results Twenty-three infants with a median (IQR) gestational age of 38.1 (36.4 – 39.0) weeks received 1828 inflations with a median Vt of 4.6 (3.3 – 6.2) ml/kg. Median Vt was in the target range in 12 infants (52%), lower in 9 (39%) and higher in 2 (9%). Thirty-six (25—27) % of the inflations were in the target rage over the duration of PPV while 42 (25 – 65) % and 10 (3 – 33) % were above and below target range. Conclusions Variability of expiratory tidal volume delivered to term and late preterm infants was wide. Reliance on standard pressures and clinical signs may be insufficient to provide safe and effective ventilation in the delivery room. Trial registration This is a secondary analysis of a prospectively registered randomized controlled trial (ACTRN12616000768493).https://doi.org/10.1186/s12887-022-03600-yTerm and late preterm infantsDelivery room stabilizationPositive pressure ventilationTidal volume |
| spellingShingle | Janine Thomann Christoph M. Rüegger Vincent D. Gaertner Eoin O’Currain Omar F. Kamlin Peter G. Davis Laila Springer Tidal volumes during delivery room stabilization of (near) term infants BMC Pediatrics Term and late preterm infants Delivery room stabilization Positive pressure ventilation Tidal volume |
| title | Tidal volumes during delivery room stabilization of (near) term infants |
| title_full | Tidal volumes during delivery room stabilization of (near) term infants |
| title_fullStr | Tidal volumes during delivery room stabilization of (near) term infants |
| title_full_unstemmed | Tidal volumes during delivery room stabilization of (near) term infants |
| title_short | Tidal volumes during delivery room stabilization of (near) term infants |
| title_sort | tidal volumes during delivery room stabilization of near term infants |
| topic | Term and late preterm infants Delivery room stabilization Positive pressure ventilation Tidal volume |
| url | https://doi.org/10.1186/s12887-022-03600-y |
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