TUBERCULOUS SPONDYLITIS IN ADULTS (clinical and radiographic manifestations)

The clinical and radiographic manifestations of maturity-onset tuberculous spondylitis were analyzed in 107 patients. If there is drug resistance in Mycobacterium tuberculosis (MBT), the extent and degree of spinal bone destruction, the extent of abscess formation, the rate of neurological disorders...

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Main Authors: N. A. Sovetova, G. Yu. Vasilyeva, N. S. Solovyeva, V. Yu. Zhuravlev, I. A. Baulin
Format: Article
Language:Russian
Published: New Terra Publishing House 2014-02-01
Series:Туберкулез и болезни лёгких
Subjects:
Online Access:https://www.tibl-journal.com/jour/article/view/31
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author N. A. Sovetova
G. Yu. Vasilyeva
N. S. Solovyeva
V. Yu. Zhuravlev
I. A. Baulin
author_facet N. A. Sovetova
G. Yu. Vasilyeva
N. S. Solovyeva
V. Yu. Zhuravlev
I. A. Baulin
author_sort N. A. Sovetova
collection DOAJ
description The clinical and radiographic manifestations of maturity-onset tuberculous spondylitis were analyzed in 107 patients. If there is drug resistance in Mycobacterium tuberculosis (MBT), the extent and degree of spinal bone destruction, the extent of abscess formation, the rate of neurological disorders are greater than those in the MBT drug sensitivity group; however, the significant difference concerns only the involvement of vertebral arches in destruction. The pattern and activity of a tuberculous process in the lung and the proportion of bacteria-excreting persons with drug resistance in MBT significantly exceed those with drug sensitivity. All the patients were operated on; the diagnosis was histologically verified in 100% of cases; the postoperative specimens exhibited MBT culture in 72.9%; the polymerase chain reaction was positive n 98.9%. Bacteriological and molecular genetic studies established multiple drug resistance in 73.4%, polyresistance in 17.3%, and monoresistance in 9.3%.
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spelling doaj.art-fc376601a48742ec9b64ec96d77cd7342023-09-03T10:34:09ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062014-02-0102101431TUBERCULOUS SPONDYLITIS IN ADULTS (clinical and radiographic manifestations)N. A. Sovetova0G. Yu. Vasilyeva1N. S. Solovyeva2V. Yu. Zhuravlev3I. A. Baulin4Санкт-Петербургский НИИ фтизиопульмонологииСанкт-Петербургский НИИ фтизиопульмонологииСанкт-Петербургский НИИ фтизиопульмонологииСанкт-Петербургский НИИ фтизиопульмонологииСанкт-Петербургский НИИ фтизиопульмонологииThe clinical and radiographic manifestations of maturity-onset tuberculous spondylitis were analyzed in 107 patients. If there is drug resistance in Mycobacterium tuberculosis (MBT), the extent and degree of spinal bone destruction, the extent of abscess formation, the rate of neurological disorders are greater than those in the MBT drug sensitivity group; however, the significant difference concerns only the involvement of vertebral arches in destruction. The pattern and activity of a tuberculous process in the lung and the proportion of bacteria-excreting persons with drug resistance in MBT significantly exceed those with drug sensitivity. All the patients were operated on; the diagnosis was histologically verified in 100% of cases; the postoperative specimens exhibited MBT culture in 72.9%; the polymerase chain reaction was positive n 98.9%. Bacteriological and molecular genetic studies established multiple drug resistance in 73.4%, polyresistance in 17.3%, and monoresistance in 9.3%.https://www.tibl-journal.com/jour/article/view/31туберкулезкостно-суставной туберкулез у взрослыхтуберкулезный спондилитклинико-лучевые проявлениялекарственная устойчивость микобактерий туберкулеза
spellingShingle N. A. Sovetova
G. Yu. Vasilyeva
N. S. Solovyeva
V. Yu. Zhuravlev
I. A. Baulin
TUBERCULOUS SPONDYLITIS IN ADULTS (clinical and radiographic manifestations)
Туберкулез и болезни лёгких
туберкулез
костно-суставной туберкулез у взрослых
туберкулезный спондилит
клинико-лучевые проявления
лекарственная устойчивость микобактерий туберкулеза
title TUBERCULOUS SPONDYLITIS IN ADULTS (clinical and radiographic manifestations)
title_full TUBERCULOUS SPONDYLITIS IN ADULTS (clinical and radiographic manifestations)
title_fullStr TUBERCULOUS SPONDYLITIS IN ADULTS (clinical and radiographic manifestations)
title_full_unstemmed TUBERCULOUS SPONDYLITIS IN ADULTS (clinical and radiographic manifestations)
title_short TUBERCULOUS SPONDYLITIS IN ADULTS (clinical and radiographic manifestations)
title_sort tuberculous spondylitis in adults clinical and radiographic manifestations
topic туберкулез
костно-суставной туберкулез у взрослых
туберкулезный спондилит
клинико-лучевые проявления
лекарственная устойчивость микобактерий туберкулеза
url https://www.tibl-journal.com/jour/article/view/31
work_keys_str_mv AT nasovetova tuberculousspondylitisinadultsclinicalandradiographicmanifestations
AT gyuvasilyeva tuberculousspondylitisinadultsclinicalandradiographicmanifestations
AT nssolovyeva tuberculousspondylitisinadultsclinicalandradiographicmanifestations
AT vyuzhuravlev tuberculousspondylitisinadultsclinicalandradiographicmanifestations
AT iabaulin tuberculousspondylitisinadultsclinicalandradiographicmanifestations