Bioprinting of Organ-on-Chip Systems: A Literature Review from a Manufacturing Perspective
This review discusses the reported studies investigating the use of bioprinting to develop functional organ-on-chip systems from a manufacturing perspective. These organ-on-chip systems model the liver, kidney, heart, lung, gut, bone, vessel, and tumors to demonstrate the viability of bioprinted org...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-08-01
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| Series: | Journal of Manufacturing and Materials Processing |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2504-4494/5/3/91 |
| _version_ | 1797518701853933568 |
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| author | Ketan Thakare Laura Jerpseth Zhijian Pei Alaa Elwany Francis Quek Hongmin Qin |
| author_facet | Ketan Thakare Laura Jerpseth Zhijian Pei Alaa Elwany Francis Quek Hongmin Qin |
| author_sort | Ketan Thakare |
| collection | DOAJ |
| description | This review discusses the reported studies investigating the use of bioprinting to develop functional organ-on-chip systems from a manufacturing perspective. These organ-on-chip systems model the liver, kidney, heart, lung, gut, bone, vessel, and tumors to demonstrate the viability of bioprinted organ-on-chip systems for disease modeling and drug screening. In addition, the paper highlights the challenges involved in using bioprinting techniques for organ-on-chip system fabrications and suggests future research directions. Based on the reviewed studies, it is concluded that bioprinting can be applied for the automated and assembly-free fabrication of organ-on chip systems. These bioprinted organ-on-chip systems can help in the modeling of several different diseases and can thereby expedite drug discovery by providing an efficient platform for drug screening in the preclinical phase of drug development processes. |
| first_indexed | 2024-03-10T07:33:26Z |
| format | Article |
| id | doaj.art-fc397cab1ac14d6492e163cae888f959 |
| institution | Directory Open Access Journal |
| issn | 2504-4494 |
| language | English |
| last_indexed | 2024-03-10T07:33:26Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Manufacturing and Materials Processing |
| spelling | doaj.art-fc397cab1ac14d6492e163cae888f9592023-11-22T13:45:03ZengMDPI AGJournal of Manufacturing and Materials Processing2504-44942021-08-01539110.3390/jmmp5030091Bioprinting of Organ-on-Chip Systems: A Literature Review from a Manufacturing PerspectiveKetan Thakare0Laura Jerpseth1Zhijian Pei2Alaa Elwany3Francis Quek4Hongmin Qin5Department of Industrial and Systems Engineering, Texas A&M University, College Station, TX 77843, USADepartment of Biology, Texas A&M University, College Station, TX 77843, USADepartment of Industrial and Systems Engineering, Texas A&M University, College Station, TX 77843, USADepartment of Industrial and Systems Engineering, Texas A&M University, College Station, TX 77843, USADepartment of Computer Science and Engineering, Texas A&M University, College Station, TX 77843, USADepartment of Biology, Texas A&M University, College Station, TX 77843, USAThis review discusses the reported studies investigating the use of bioprinting to develop functional organ-on-chip systems from a manufacturing perspective. These organ-on-chip systems model the liver, kidney, heart, lung, gut, bone, vessel, and tumors to demonstrate the viability of bioprinted organ-on-chip systems for disease modeling and drug screening. In addition, the paper highlights the challenges involved in using bioprinting techniques for organ-on-chip system fabrications and suggests future research directions. Based on the reviewed studies, it is concluded that bioprinting can be applied for the automated and assembly-free fabrication of organ-on chip systems. These bioprinted organ-on-chip systems can help in the modeling of several different diseases and can thereby expedite drug discovery by providing an efficient platform for drug screening in the preclinical phase of drug development processes.https://www.mdpi.com/2504-4494/5/3/91additive manufacturingbioprintingorgan-on-chip |
| spellingShingle | Ketan Thakare Laura Jerpseth Zhijian Pei Alaa Elwany Francis Quek Hongmin Qin Bioprinting of Organ-on-Chip Systems: A Literature Review from a Manufacturing Perspective Journal of Manufacturing and Materials Processing additive manufacturing bioprinting organ-on-chip |
| title | Bioprinting of Organ-on-Chip Systems: A Literature Review from a Manufacturing Perspective |
| title_full | Bioprinting of Organ-on-Chip Systems: A Literature Review from a Manufacturing Perspective |
| title_fullStr | Bioprinting of Organ-on-Chip Systems: A Literature Review from a Manufacturing Perspective |
| title_full_unstemmed | Bioprinting of Organ-on-Chip Systems: A Literature Review from a Manufacturing Perspective |
| title_short | Bioprinting of Organ-on-Chip Systems: A Literature Review from a Manufacturing Perspective |
| title_sort | bioprinting of organ on chip systems a literature review from a manufacturing perspective |
| topic | additive manufacturing bioprinting organ-on-chip |
| url | https://www.mdpi.com/2504-4494/5/3/91 |
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