How to Find the Right RNA-Sensing CRISPR-Cas System for an <i>In Vitro</i> Application

How to Find the Right RNA-Sensing CRISPR-Cas System for an <i>In Vitro</i> Application

CRISPR-Cas systems have a great and still largely untapped potential for <i>in vitro</i> applications, in particular, for RNA biosensing. However, there is currently no systematic guide on selecting the most appropriate RNA-targeting CRISPR-Cas system for a given application among thousa...

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Bibliographic Details
Main Authors: Escarlet Díaz-Galicia, Raik Grünberg, Stefan T. Arold
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Biosensors
Subjects:
RNA sensing
CRISPR-Cas
spacer
<i>in vitro</i>
PAM
sensor design
Online Access:https://www.mdpi.com/2079-6374/12/2/53

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