Intractable complicated course of tricuspid valve infective endocarditis due to non-compliance of treatment with clinical guidelines with a decisive role of molecular biological study in etiological diagnosis: a case report
A clinical observation of the treatment non-compliance consequences with clinical guidelines and principles of empirical therapy selection in a female patient with intravenous drug abuse, viral hepatitis C and HIV infection, with a history of a COVID-19 and the development of uncontrolled staphyloco...
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| Format: | Article |
| Language: | English |
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Столичная издательская компания
2023-07-01
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| Series: | Рациональная фармакотерапия в кардиологии |
| Subjects: | |
| Online Access: | https://www.rpcardio.online/jour/article/view/2689 |
| _version_ | 1826949555907723264 |
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| author | E. O. Kotova A. Yu. Moiseeva E. A. Domonova O. Yu. Silveytrova A. S. Pisaryuk P. V. Kakhktsyan J. I. Babukhina Zh. D. Kobalava |
| author_facet | E. O. Kotova A. Yu. Moiseeva E. A. Domonova O. Yu. Silveytrova A. S. Pisaryuk P. V. Kakhktsyan J. I. Babukhina Zh. D. Kobalava |
| author_sort | E. O. Kotova |
| collection | DOAJ |
| description | A clinical observation of the treatment non-compliance consequences with clinical guidelines and principles of empirical therapy selection in a female patient with intravenous drug abuse, viral hepatitis C and HIV infection, with a history of a COVID-19 and the development of uncontrolled staphylococcal infective endocarditis (IE) of the tricuspid valve, complicated recurrence of early prosthetic IE is presented. Successful treatment was achieved only by a combination of tricuspid valve replacement and the appointment of etiotropic therapy for S. aureus (MSSA). The typical clinical scenario was not accompanied by the choice of adequate empirical antibiotic therapy, despite the high suspicion of association with MSSA, which determined the complicated course of IE. Only the polymerase chain reaction of the heart valve tissue played a key role in the etiological diagnosis. The use of valve tissue polymerase chain reaction in addition to traditional microbiological methods is a valuable diagnostic study. |
| first_indexed | 2024-03-08T14:00:38Z |
| format | Article |
| id | doaj.art-fc3b43bd237c4a1ca38f56699229c9a5 |
| institution | Directory Open Access Journal |
| issn | 1819-6446 2225-3653 |
| language | English |
| last_indexed | 2025-02-17T22:15:59Z |
| publishDate | 2023-07-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj.art-fc3b43bd237c4a1ca38f56699229c9a52024-12-04T11:48:22ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532023-07-0119324024710.20996/1819-6446-2023-26892120Intractable complicated course of tricuspid valve infective endocarditis due to non-compliance of treatment with clinical guidelines with a decisive role of molecular biological study in etiological diagnosis: a case reportE. O. Kotova0A. Yu. Moiseeva1E. A. Domonova2O. Yu. Silveytrova3A. S. Pisaryuk4P. V. Kakhktsyan5J. I. Babukhina6Zh. D. Kobalava7Peoples’ Friendship University of Russia (RUDN), Medical Institute; V.V. Vinogradov City HospitalPeoples’ Friendship University of Russia (RUDN), Medical InstituteCentral Research Institute of EpidemiologyCentral Research Institute of EpidemiologyPeoples’ Friendship University of Russia (RUDN), Medical Institute; V.V. Vinogradov City HospitalA.N. Bakulev National Medical Research Center of Cardiovascular SurgeryA.N. Bakulev National Medical Research Center of Cardiovascular SurgeryPeoples’ Friendship University of Russia (RUDN), Medical Institute; V.V. Vinogradov City HospitalA clinical observation of the treatment non-compliance consequences with clinical guidelines and principles of empirical therapy selection in a female patient with intravenous drug abuse, viral hepatitis C and HIV infection, with a history of a COVID-19 and the development of uncontrolled staphylococcal infective endocarditis (IE) of the tricuspid valve, complicated recurrence of early prosthetic IE is presented. Successful treatment was achieved only by a combination of tricuspid valve replacement and the appointment of etiotropic therapy for S. aureus (MSSA). The typical clinical scenario was not accompanied by the choice of adequate empirical antibiotic therapy, despite the high suspicion of association with MSSA, which determined the complicated course of IE. Only the polymerase chain reaction of the heart valve tissue played a key role in the etiological diagnosis. The use of valve tissue polymerase chain reaction in addition to traditional microbiological methods is a valuable diagnostic study.https://www.rpcardio.online/jour/article/view/2689infective endocarditispolymerase chain reactionvalve pcrintravenous drug addictionclinical guidelinesantibiotic therapy |
| spellingShingle | E. O. Kotova A. Yu. Moiseeva E. A. Domonova O. Yu. Silveytrova A. S. Pisaryuk P. V. Kakhktsyan J. I. Babukhina Zh. D. Kobalava Intractable complicated course of tricuspid valve infective endocarditis due to non-compliance of treatment with clinical guidelines with a decisive role of molecular biological study in etiological diagnosis: a case report Рациональная фармакотерапия в кардиологии infective endocarditis polymerase chain reaction valve pcr intravenous drug addiction clinical guidelines antibiotic therapy |
| title | Intractable complicated course of tricuspid valve infective endocarditis due to non-compliance of treatment with clinical guidelines with a decisive role of molecular biological study in etiological diagnosis: a case report |
| title_full | Intractable complicated course of tricuspid valve infective endocarditis due to non-compliance of treatment with clinical guidelines with a decisive role of molecular biological study in etiological diagnosis: a case report |
| title_fullStr | Intractable complicated course of tricuspid valve infective endocarditis due to non-compliance of treatment with clinical guidelines with a decisive role of molecular biological study in etiological diagnosis: a case report |
| title_full_unstemmed | Intractable complicated course of tricuspid valve infective endocarditis due to non-compliance of treatment with clinical guidelines with a decisive role of molecular biological study in etiological diagnosis: a case report |
| title_short | Intractable complicated course of tricuspid valve infective endocarditis due to non-compliance of treatment with clinical guidelines with a decisive role of molecular biological study in etiological diagnosis: a case report |
| title_sort | intractable complicated course of tricuspid valve infective endocarditis due to non compliance of treatment with clinical guidelines with a decisive role of molecular biological study in etiological diagnosis a case report |
| topic | infective endocarditis polymerase chain reaction valve pcr intravenous drug addiction clinical guidelines antibiotic therapy |
| url | https://www.rpcardio.online/jour/article/view/2689 |
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