Molecular characterization based on tumor microenvironment-related signatures for guiding immunotherapy and therapeutic resistance in lung adenocarcinoma

Molecular characterization based on tumor microenvironment-related signatures for guiding immunotherapy and therapeutic resistance in lung adenocarcinoma

Background: Although the role of tumor microenvironment in lung adenocarcinoma (LUAD) has been explored in a number of studies, the value of TME-related signatures in immunotherapy has not been comprehensively characterized.Materials and Methods: Consensus clustering was conducted to characterize TM...

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Bibliographic Details
Main Authors: Yamin Jie, Jianing Wu, Dongxue An, Man Li, Hongjiang He, Duo Wang, Anxin Gu, Mingyan E
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Pharmacology
Subjects:
lung adenocarcinoma
molecular subtypes
immunotherapy
cisplatin
paclitaxel
DNA methylation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1099927/full

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