Spatial transcriptomic brain imaging reveals the effects of immunomodulation therapy on specific regional brain cells in a mouse dementia model

Abstract Increasing evidence of brain-immune crosstalk raises expectations for the efficacy of novel immunotherapies in Alzheimer’s disease (AD), but the lack of methods to examine brain tissues makes it difficult to evaluate therapeutics. Here, we investigated the changes in spatial transcriptomic...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Eun Ji Lee, Minseok Suh, Hongyoon Choi, Yoori Choi, Do Won Hwang, Sungwoo Bae, Dong Soo Lee
Formatua: Artikulua
Hizkuntza:English
Argitaratua: BMC 2024-05-01
Saila:BMC Genomics
Gaiak:
Sarrera elektronikoa:https://doi.org/10.1186/s12864-024-10434-8