Development and proof-of-concept demonstration of a clinical metagenomics method for the rapid detection of bloodstream infection

Development and proof-of-concept demonstration of a clinical metagenomics method for the rapid detection of bloodstream infection

Abstract Background The timely and accurate diagnosis of bloodstream infection (BSI) is critical for patient management. With longstanding challenges for routine blood culture, metagenomics is a promising approach to rapidly provide sequence-based detection and characterisation of bloodborne bacteri...

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Bibliographic Details
Main Authors: Lluis Moragues-Solanas, Thanh Le-Viet, Elinor McSorley, Carl Halford, Daniel S. Lockhart, Alp Aydin, Gemma L. Kay, Ngozi Elumogo, William Mullen, Justin O’Grady, Matthew W. Gilmour
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Medical Genomics
Subjects:
Clinical diagnostics
Metagenomics
Bacteraemia
Sepsis
Bacterial infection
Long-read sequencing
Online Access:https://doi.org/10.1186/s12920-024-01835-5

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