Management of Leiomyosarcoma of the Prostate: Unraveling a Hoax

Prostatic Leiomyosarcoma is a rare tumor with less than 200 cases reported. These are aggressive tumors and treatment guidelines are not well established. In early stages, they usually present with obstructive lower urinary tract symptoms without elevation of serum prostate-specific antigen. They la...

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Main Authors: Dr. Dharma Ram Poonia, Dr. Amitabh Singh, Sunil H, Dr. Jatin Gandhi, Dr. Sudhir Rawal
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Current Problems in Cancer: Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S266662192100017X
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author Dr. Dharma Ram Poonia
Dr. Amitabh Singh
Sunil H
Dr. Jatin Gandhi
Dr. Sudhir Rawal
author_facet Dr. Dharma Ram Poonia
Dr. Amitabh Singh
Sunil H
Dr. Jatin Gandhi
Dr. Sudhir Rawal
author_sort Dr. Dharma Ram Poonia
collection DOAJ
description Prostatic Leiomyosarcoma is a rare tumor with less than 200 cases reported. These are aggressive tumors and treatment guidelines are not well established. In early stages, they usually present with obstructive lower urinary tract symptoms without elevation of serum prostate-specific antigen. They lack specific clinical or imaging characteristics, hence keeping a high degree of skepticism might aid in timely detection. The early-stage disease can be managed with surgery and radiotherapy with relatively modest survival. Here we are reporting a case of primary prostatic leiomyosarcoma with some insight into diagnostic issues and disease biology with basic management principles. We have developed a treatment algorithm based on available literature.
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spelling doaj.art-fc3f28a99564429babdb874aeba3fb022022-12-21T18:41:07ZengElsevierCurrent Problems in Cancer: Case Reports2666-62192021-03-013100068Management of Leiomyosarcoma of the Prostate: Unraveling a HoaxDr. Dharma Ram Poonia0Dr. Amitabh Singh1 Sunil H2Dr. Jatin Gandhi3Dr. Sudhir Rawal4Department of Surgical Oncology, All India Institute of Medical Sciences, Jodhpur, India; Corresponding author.Department of Uro-Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New DelhiDepartment of Surgical Oncology, All India Institute of Medical Sciences, Rishikesh, IndiaDepartment of Pathology, Rajiv Gandhi Cancer Institute and Research Centre, New DelhiDirector and head of Uro-Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New DelhiProstatic Leiomyosarcoma is a rare tumor with less than 200 cases reported. These are aggressive tumors and treatment guidelines are not well established. In early stages, they usually present with obstructive lower urinary tract symptoms without elevation of serum prostate-specific antigen. They lack specific clinical or imaging characteristics, hence keeping a high degree of skepticism might aid in timely detection. The early-stage disease can be managed with surgery and radiotherapy with relatively modest survival. Here we are reporting a case of primary prostatic leiomyosarcoma with some insight into diagnostic issues and disease biology with basic management principles. We have developed a treatment algorithm based on available literature.http://www.sciencedirect.com/science/article/pii/S266662192100017XProstatic sarcomaProstate LMSProstatectomyRare
spellingShingle Dr. Dharma Ram Poonia
Dr. Amitabh Singh
Sunil H
Dr. Jatin Gandhi
Dr. Sudhir Rawal
Management of Leiomyosarcoma of the Prostate: Unraveling a Hoax
Current Problems in Cancer: Case Reports
Prostatic sarcoma
Prostate LMS
Prostatectomy
Rare
title Management of Leiomyosarcoma of the Prostate: Unraveling a Hoax
title_full Management of Leiomyosarcoma of the Prostate: Unraveling a Hoax
title_fullStr Management of Leiomyosarcoma of the Prostate: Unraveling a Hoax
title_full_unstemmed Management of Leiomyosarcoma of the Prostate: Unraveling a Hoax
title_short Management of Leiomyosarcoma of the Prostate: Unraveling a Hoax
title_sort management of leiomyosarcoma of the prostate unraveling a hoax
topic Prostatic sarcoma
Prostate LMS
Prostatectomy
Rare
url http://www.sciencedirect.com/science/article/pii/S266662192100017X
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