Analysis of Biochemical and Hematological Parameters During the First and Second Wave of SARS-CoV-2 Infection among North-East Indian Cancer Patients
Introduction: SARS-CoV-2 (COVID-19) affects respiratory airways as well as the kidneys, hearts etc. This study aims to demonstrate the impact of COVID-19 infection on biochemical and hematological parameters in cancer patients of North-East India. Methods: The study includes biochemical parameters...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
West Asia Organization for Cancer Prevention
2022-11-01
|
| Series: | Asian Pacific Journal of Cancer Care |
| Subjects: | |
| Online Access: | http://www.waocp.com/journal/index.php/apjcc/article/view/906 |
| _version_ | 1827370949599559680 |
|---|---|
| author | Sawmik Das Anupam Sarma Biki Chandra Das Dhruba Jyoti Sarma Rashmisnata Barman Mouchumee Bhattacharyya Amal Chandra Kataki Avdhesh Kumar Rai |
| author_facet | Sawmik Das Anupam Sarma Biki Chandra Das Dhruba Jyoti Sarma Rashmisnata Barman Mouchumee Bhattacharyya Amal Chandra Kataki Avdhesh Kumar Rai |
| author_sort | Sawmik Das |
| collection | DOAJ |
| description | Introduction: SARS-CoV-2 (COVID-19) affects respiratory airways as well as the kidneys, hearts etc. This study aims to demonstrate the impact of COVID-19 infection on biochemical and hematological parameters in cancer patients of North-East India.
Methods: The study includes biochemical parameters for 907 and hematological parameters for 1103 cancer patients who were tested for COVID-19 between 1st June 2020 and 1st June 2021. All the data were analyzed by the statistical software SPSS (ver20).
Results: AST (p = 0.023), GGT (p = 0.026) and Urea (p = 0.004) significantly increased in COVID-19 positive cancer patients compared to negative cancer patients. Eosinophils (p=0.01), eosinophils absolute (p=0.01), monocyte (p=0.04) and MCHC (p=0.01) were significantly decreased in COVID-19 positive cancer patients compared to negative. Various biochemical and haematological parameters analysed in our study were found to be altered between the COVID-19 positive and negative group but their association was not found to be statistically significant.
Conclusion: We conclude that in cancer patients of North-East India, significant alterations of biochemical and hematological parameters AST, GGT, Urea, Eosinophils, eosinophils absolute, monocyte and MCHC were found in COVID-19 positive cancer patients compared to negative cancer patients. |
| first_indexed | 2024-03-08T10:31:03Z |
| format | Article |
| id | doaj.art-fc43b8840c38490693d48621038cdcb1 |
| institution | Directory Open Access Journal |
| issn | 2588-3682 |
| language | English |
| last_indexed | 2024-03-08T10:31:03Z |
| publishDate | 2022-11-01 |
| publisher | West Asia Organization for Cancer Prevention |
| record_format | Article |
| series | Asian Pacific Journal of Cancer Care |
| spelling | doaj.art-fc43b8840c38490693d48621038cdcb12024-01-27T05:51:06ZengWest Asia Organization for Cancer PreventionAsian Pacific Journal of Cancer Care2588-36822022-11-017463764210.31557/apjcc.2022.7.4.637-642906Analysis of Biochemical and Hematological Parameters During the First and Second Wave of SARS-CoV-2 Infection among North-East Indian Cancer PatientsSawmik Das0Anupam Sarma1Biki Chandra Das2Dhruba Jyoti Sarma3Rashmisnata Barman4Mouchumee Bhattacharyya5Amal Chandra Kataki6Avdhesh Kumar Rai7Department of Biochemistry, Dr B Borooah Cancer Institute, Gopinath Nagar, Guwahati 781016, Assam, India.Department of Oncopathology, Dr B Borooah Cancer Institute, Gopinath Nagar, Guwahati 781016, Assam, India.DBT Centre for Molecular Biology and Cancer Research, Dr B Barooah Cancer Institute, Gopinath Nagar, Guwahati 781016, India.DBT Centre for Molecular Biology and Cancer Research, Dr B Barooah Cancer Institute, Gopinath Nagar, Guwahati 781016Department of Microbiology, Dr B Borooah Cancer Institute, Gopinath Nagar, Guwahati 781016, Assam, India.Department of Radiation Oncology, Dr B Borooah Cancer Institute, Gopinath Nagar, Guwahati 781016, Assam, India.Department of Gynaecologic Oncology, Dr B Borooah Cancer Institute, Gopinath Nagar, Guwahati 781016, Assam, India.DBT Centre for Molecular Biology and Cancer Research, Dr B Barooah Cancer Institute, Gopinath Nagar, Guwahati 781016, India.Introduction: SARS-CoV-2 (COVID-19) affects respiratory airways as well as the kidneys, hearts etc. This study aims to demonstrate the impact of COVID-19 infection on biochemical and hematological parameters in cancer patients of North-East India. Methods: The study includes biochemical parameters for 907 and hematological parameters for 1103 cancer patients who were tested for COVID-19 between 1st June 2020 and 1st June 2021. All the data were analyzed by the statistical software SPSS (ver20). Results: AST (p = 0.023), GGT (p = 0.026) and Urea (p = 0.004) significantly increased in COVID-19 positive cancer patients compared to negative cancer patients. Eosinophils (p=0.01), eosinophils absolute (p=0.01), monocyte (p=0.04) and MCHC (p=0.01) were significantly decreased in COVID-19 positive cancer patients compared to negative. Various biochemical and haematological parameters analysed in our study were found to be altered between the COVID-19 positive and negative group but their association was not found to be statistically significant. Conclusion: We conclude that in cancer patients of North-East India, significant alterations of biochemical and hematological parameters AST, GGT, Urea, Eosinophils, eosinophils absolute, monocyte and MCHC were found in COVID-19 positive cancer patients compared to negative cancer patients.http://www.waocp.com/journal/index.php/apjcc/article/view/906sars-cov-2cancerbiochemical parametershematological parameters |
| spellingShingle | Sawmik Das Anupam Sarma Biki Chandra Das Dhruba Jyoti Sarma Rashmisnata Barman Mouchumee Bhattacharyya Amal Chandra Kataki Avdhesh Kumar Rai Analysis of Biochemical and Hematological Parameters During the First and Second Wave of SARS-CoV-2 Infection among North-East Indian Cancer Patients Asian Pacific Journal of Cancer Care sars-cov-2 cancer biochemical parameters hematological parameters |
| title | Analysis of Biochemical and Hematological Parameters During the First and Second Wave of SARS-CoV-2 Infection among North-East Indian Cancer Patients |
| title_full | Analysis of Biochemical and Hematological Parameters During the First and Second Wave of SARS-CoV-2 Infection among North-East Indian Cancer Patients |
| title_fullStr | Analysis of Biochemical and Hematological Parameters During the First and Second Wave of SARS-CoV-2 Infection among North-East Indian Cancer Patients |
| title_full_unstemmed | Analysis of Biochemical and Hematological Parameters During the First and Second Wave of SARS-CoV-2 Infection among North-East Indian Cancer Patients |
| title_short | Analysis of Biochemical and Hematological Parameters During the First and Second Wave of SARS-CoV-2 Infection among North-East Indian Cancer Patients |
| title_sort | analysis of biochemical and hematological parameters during the first and second wave of sars cov 2 infection among north east indian cancer patients |
| topic | sars-cov-2 cancer biochemical parameters hematological parameters |
| url | http://www.waocp.com/journal/index.php/apjcc/article/view/906 |
| work_keys_str_mv | AT sawmikdas analysisofbiochemicalandhematologicalparametersduringthefirstandsecondwaveofsarscov2infectionamongnortheastindiancancerpatients AT anupamsarma analysisofbiochemicalandhematologicalparametersduringthefirstandsecondwaveofsarscov2infectionamongnortheastindiancancerpatients AT bikichandradas analysisofbiochemicalandhematologicalparametersduringthefirstandsecondwaveofsarscov2infectionamongnortheastindiancancerpatients AT dhrubajyotisarma analysisofbiochemicalandhematologicalparametersduringthefirstandsecondwaveofsarscov2infectionamongnortheastindiancancerpatients AT rashmisnatabarman analysisofbiochemicalandhematologicalparametersduringthefirstandsecondwaveofsarscov2infectionamongnortheastindiancancerpatients AT mouchumeebhattacharyya analysisofbiochemicalandhematologicalparametersduringthefirstandsecondwaveofsarscov2infectionamongnortheastindiancancerpatients AT amalchandrakataki analysisofbiochemicalandhematologicalparametersduringthefirstandsecondwaveofsarscov2infectionamongnortheastindiancancerpatients AT avdheshkumarrai analysisofbiochemicalandhematologicalparametersduringthefirstandsecondwaveofsarscov2infectionamongnortheastindiancancerpatients |