Umbilical nucleated red blood cell as a sign of fetal distress
Background: The presence of increased numbers of nucleated red blood cell (NRBC) in the umbilical cord blood has been associated with states of relative hypoxia. Nucleated red blood cell counts are a potentially useful tool in estimating the degree and timing of intrauterine hypoxia. This may have i...
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| Format: | Article |
| Language: | fas |
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Tehran University of Medical Sciences
2008-06-01
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| Series: | Tehran University Medical Journal |
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| Online Access: | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/6741.pdf&manuscript_id=6741 |
| _version_ | 1819327070397792256 |
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| author | Torkestani F Zafarghndi N Hadavand SH Zaery F Bozorg ghomi M |
| author_facet | Torkestani F Zafarghndi N Hadavand SH Zaery F Bozorg ghomi M |
| author_sort | Torkestani F |
| collection | DOAJ |
| description | Background: The presence of increased numbers of nucleated red blood cell (NRBC) in the umbilical cord blood has been associated with states of relative hypoxia. Nucleated red blood cell counts are a potentially useful tool in estimating the degree and timing of intrauterine hypoxia. This may have important implication in determining causality in case of compromised infant. Cord blood NRBC counts may be obtained noninvasively from an otherwise discarded specimen and analyzed by personnel on equipment readily available in most hospital laboratories. Since the aim of monitoring of fetal heart is early diagnosis of hypoxia, we studied the relationship between abnormal fetal heart rate with the number of nucleated red blood cells (NRBC) in the umbilical cord blood.Methods: We performed this research at Hazrat Zeynab Hospital on 130 full-term newborns (65 cases of fetal distress and 65 normal cases) between July 2005 and July 2006. The NRBC counts of newborns with abnormal fetal heart rate were compared with those of normal newborns and correlations with other parameters including Apgar score, hemoglobin level, condition of newborns in the first 24 hours of the birth and birth weight.Results: The mean NRBC count in the fetal distress group was 9.45 ± 8.75 and that of the normal group was 9.17 ± 8.76 per 100 white cells (p=0.89). The mean duration between diagnosis of fetal distress to birth was equal to 1.2± 0.77 hours. Furthermore, there was no meaningful correlation between number of NRBC and Apgar score, hemoglobin, birth weight and condition of newborns in the first 24 hours.Conclusion: If the fetus is born a short time after the diagnosis of distress with no risk factors for hypoxia, the NRBC count for cord blood is not elevated. |
| first_indexed | 2024-12-24T13:05:00Z |
| format | Article |
| id | doaj.art-fc48794eeb304861802636f35a4dc002 |
| institution | Directory Open Access Journal |
| issn | 1683-1764 1735-7322 |
| language | fas |
| last_indexed | 2024-12-24T13:05:00Z |
| publishDate | 2008-06-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Tehran University Medical Journal |
| spelling | doaj.art-fc48794eeb304861802636f35a4dc0022022-12-21T16:54:02ZfasTehran University of Medical SciencesTehran University Medical Journal1683-17641735-73222008-06-016612933Umbilical nucleated red blood cell as a sign of fetal distressTorkestani FZafarghndi NHadavand SHZaery FBozorg ghomi MBackground: The presence of increased numbers of nucleated red blood cell (NRBC) in the umbilical cord blood has been associated with states of relative hypoxia. Nucleated red blood cell counts are a potentially useful tool in estimating the degree and timing of intrauterine hypoxia. This may have important implication in determining causality in case of compromised infant. Cord blood NRBC counts may be obtained noninvasively from an otherwise discarded specimen and analyzed by personnel on equipment readily available in most hospital laboratories. Since the aim of monitoring of fetal heart is early diagnosis of hypoxia, we studied the relationship between abnormal fetal heart rate with the number of nucleated red blood cells (NRBC) in the umbilical cord blood.Methods: We performed this research at Hazrat Zeynab Hospital on 130 full-term newborns (65 cases of fetal distress and 65 normal cases) between July 2005 and July 2006. The NRBC counts of newborns with abnormal fetal heart rate were compared with those of normal newborns and correlations with other parameters including Apgar score, hemoglobin level, condition of newborns in the first 24 hours of the birth and birth weight.Results: The mean NRBC count in the fetal distress group was 9.45 ± 8.75 and that of the normal group was 9.17 ± 8.76 per 100 white cells (p=0.89). The mean duration between diagnosis of fetal distress to birth was equal to 1.2± 0.77 hours. Furthermore, there was no meaningful correlation between number of NRBC and Apgar score, hemoglobin, birth weight and condition of newborns in the first 24 hours.Conclusion: If the fetus is born a short time after the diagnosis of distress with no risk factors for hypoxia, the NRBC count for cord blood is not elevated.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/6741.pdf&manuscript_id=6741nRBCfetal distressfetal hypoxyfetal heart rate |
| spellingShingle | Torkestani F Zafarghndi N Hadavand SH Zaery F Bozorg ghomi M Umbilical nucleated red blood cell as a sign of fetal distress Tehran University Medical Journal nRBC fetal distress fetal hypoxy fetal heart rate |
| title | Umbilical nucleated red blood cell as a sign of fetal distress |
| title_full | Umbilical nucleated red blood cell as a sign of fetal distress |
| title_fullStr | Umbilical nucleated red blood cell as a sign of fetal distress |
| title_full_unstemmed | Umbilical nucleated red blood cell as a sign of fetal distress |
| title_short | Umbilical nucleated red blood cell as a sign of fetal distress |
| title_sort | umbilical nucleated red blood cell as a sign of fetal distress |
| topic | nRBC fetal distress fetal hypoxy fetal heart rate |
| url | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/6741.pdf&manuscript_id=6741 |
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