Age-related differences in ventral striatal and default mode network function during reciprocated trust
Social relationships change across the lifespan as social networks narrow and motivational priorities shift to the present. Interestingly, aging is also associated with changes in executive function, including decision-making abilities, but it remains unclear how age-related changes in both domains...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-08-01
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| Series: | NeuroImage |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1053811922003883 |
| _version_ | 1811341139429556224 |
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| author | Dominic S. Fareri Katherine Hackett Lindsey J. Tepfer Victoria Kelly Nicole Henninger Crystal Reeck Tania Giovannetti David V. Smith |
| author_facet | Dominic S. Fareri Katherine Hackett Lindsey J. Tepfer Victoria Kelly Nicole Henninger Crystal Reeck Tania Giovannetti David V. Smith |
| author_sort | Dominic S. Fareri |
| collection | DOAJ |
| description | Social relationships change across the lifespan as social networks narrow and motivational priorities shift to the present. Interestingly, aging is also associated with changes in executive function, including decision-making abilities, but it remains unclear how age-related changes in both domains interact to impact financial decisions involving other people. To study this problem, we recruited 50 human participants (Nyounger = 26, ages 18–34; Nolder = 24, ages 63–80) to play an economic trust game as the investor with three partners (friend, stranger, and computer) who played the role of investee. Investors underwent functional magnetic resonance imaging (fMRI) during the trust game while investees were seated outside of the scanner. Building on our previous work with younger adults showing both enhanced striatal responses and altered default-mode network (DMN) connectivity as a function of social closeness during reciprocated trust, we predicted that these relations would exhibit age-related differences. We found that striatal responses to reciprocated trust from friends relative to strangers and computers were blunted in older adults relative to younger adults, thus supporting our primary pre-registered hypothesis regarding social closeness. We also found that older adults exhibited enhanced DMN connectivity with the temporoparietal junction (TPJ) during reciprocated trust from friends compared to computers while younger adults exhibited the opposite pattern. Taken together, these results advance our understanding of age-related differences in sensitivity to social closeness in the context of trusting others. |
| first_indexed | 2024-04-13T18:52:20Z |
| format | Article |
| id | doaj.art-fc48babc7bd84b178479abc3885780fa |
| institution | Directory Open Access Journal |
| issn | 1095-9572 |
| language | English |
| last_indexed | 2024-04-13T18:52:20Z |
| publishDate | 2022-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | NeuroImage |
| spelling | doaj.art-fc48babc7bd84b178479abc3885780fa2022-12-22T02:34:23ZengElsevierNeuroImage1095-95722022-08-01256119267Age-related differences in ventral striatal and default mode network function during reciprocated trustDominic S. Fareri0Katherine Hackett1Lindsey J. Tepfer2Victoria Kelly3Nicole Henninger4Crystal Reeck5Tania Giovannetti6David V. Smith7Gordon F. Derner School of Psychology, Adelphi University, Garden City, NY, USA; Corresponding authors.Department of Psychology and Neuroscience, Temple University, Philadelphia, PA, USADepartment of Psychological and Brain Sciences, Dartmouth College, Hanover, NH, USADepartment of Psychology and Neuroscience, Temple University, Philadelphia, PA, USALew Klein College of Media and Communication, Temple University, Philadelphia, PA, USAFox School of Business, Temple University, Philadelphia, PA, USADepartment of Psychology and Neuroscience, Temple University, Philadelphia, PA, USADepartment of Psychology and Neuroscience, Temple University, Philadelphia, PA, USA; Corresponding authors.Social relationships change across the lifespan as social networks narrow and motivational priorities shift to the present. Interestingly, aging is also associated with changes in executive function, including decision-making abilities, but it remains unclear how age-related changes in both domains interact to impact financial decisions involving other people. To study this problem, we recruited 50 human participants (Nyounger = 26, ages 18–34; Nolder = 24, ages 63–80) to play an economic trust game as the investor with three partners (friend, stranger, and computer) who played the role of investee. Investors underwent functional magnetic resonance imaging (fMRI) during the trust game while investees were seated outside of the scanner. Building on our previous work with younger adults showing both enhanced striatal responses and altered default-mode network (DMN) connectivity as a function of social closeness during reciprocated trust, we predicted that these relations would exhibit age-related differences. We found that striatal responses to reciprocated trust from friends relative to strangers and computers were blunted in older adults relative to younger adults, thus supporting our primary pre-registered hypothesis regarding social closeness. We also found that older adults exhibited enhanced DMN connectivity with the temporoparietal junction (TPJ) during reciprocated trust from friends compared to computers while younger adults exhibited the opposite pattern. Taken together, these results advance our understanding of age-related differences in sensitivity to social closeness in the context of trusting others.http://www.sciencedirect.com/science/article/pii/S1053811922003883TrustReciprocityAgingVentral striatumDefault mode networkConnectivity |
| spellingShingle | Dominic S. Fareri Katherine Hackett Lindsey J. Tepfer Victoria Kelly Nicole Henninger Crystal Reeck Tania Giovannetti David V. Smith Age-related differences in ventral striatal and default mode network function during reciprocated trust NeuroImage Trust Reciprocity Aging Ventral striatum Default mode network Connectivity |
| title | Age-related differences in ventral striatal and default mode network function during reciprocated trust |
| title_full | Age-related differences in ventral striatal and default mode network function during reciprocated trust |
| title_fullStr | Age-related differences in ventral striatal and default mode network function during reciprocated trust |
| title_full_unstemmed | Age-related differences in ventral striatal and default mode network function during reciprocated trust |
| title_short | Age-related differences in ventral striatal and default mode network function during reciprocated trust |
| title_sort | age related differences in ventral striatal and default mode network function during reciprocated trust |
| topic | Trust Reciprocity Aging Ventral striatum Default mode network Connectivity |
| url | http://www.sciencedirect.com/science/article/pii/S1053811922003883 |
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