Mechanism of blood-brain barrier damage caused by the inhibition of Wnt7/β-catenin pathway induced by endoplasmic reticulum stress in cerebrovascular endothelial cells after stroke

Mechanism of blood-brain barrier damage caused by the inhibition of Wnt7/β-catenin pathway induced by endoplasmic reticulum stress in cerebrovascular endothelial cells after stroke

Objective·To investigate whether the inactivation of Wnt7/β-catenin signaling causes the destruction of the blood-brain barrier (BBB) in cerebrovascular endothelial cells after ischemic stroke, and investigate whether endoplasmic reticulum stress bursts mediates the inhibition of Wnt7/β-catenin path...

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Bibliographic Details
Main Authors: DONG Haiping, XIE Haiyi, MA Xiaoxiao, WANG Zhenhong
Format: Article
Language:zho
Published: Editorial Office of Journal of Shanghai Jiao Tong University (Medical Science) 2023-07-01
Series:Shanghai Jiaotong Daxue xuebao. Yixue ban
Subjects:
endoplasmic reticulum stress
wnt7/β-catenin pathway
blood-brain barrier (bbb)
ischemic stroke
Online Access:https://xuebao.shsmu.edu.cn/article/2023/1674-8115/1674-8115-2023-43-7-829.shtml

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