Study on Mechanical Properties and Degradation Behavior of Magnesium Alloy Vascular Clip
The Mg alloy vascular clip has biodegradability and good biocompatibility, which can improve the convenience and safety of clinical application. However, the Mg alloy vascular clip also has some disadvantages, such as an unreasonable structure design and a degradation rate which is too fast. In this...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-10-01
|
| Series: | Journal of Functional Biomaterials |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-4983/14/10/501 |
| _version_ | 1797573425604067328 |
|---|---|
| author | Hongxu Zhang Ming Gao Xiaoying Tian Dali Cao Lili Tan |
| author_facet | Hongxu Zhang Ming Gao Xiaoying Tian Dali Cao Lili Tan |
| author_sort | Hongxu Zhang |
| collection | DOAJ |
| description | The Mg alloy vascular clip has biodegradability and good biocompatibility, which can improve the convenience and safety of clinical application. However, the Mg alloy vascular clip also has some disadvantages, such as an unreasonable structure design and a degradation rate which is too fast. In this study, the process of clamping blood vessels with a biodegradable Mg alloy (Mg-Zn-Nd-Zr and Mg-Zn-Nd) general V-type vascular clip was simulated by finite element simulation software (Abaqus). A new type of vascular clip, the P-type vascular clip, was analyzed and investigated through simulation. The differences between Mg alloy vascular clips of V-type and P-type were analyzed by finite element simulation. In addition, the effects of Zr element on the mechanical properties and corrosion resistance of P-type vascular clips were also investigated to improve the mechanical stability. The results show that during the V-type vascular clip closure of Mg-Zn-Nd-Zr alloy, this clip has some problems, such as uneven distribution of blood vessel stress, crevices in blood vessels and stress concentration. The improved P-type vascular clip has uniform closure, and there is no gap in the blood vessel, which can effectively avoid stress concentration. The improved P-type vascular clip is well closed and can effectively avoid stress concentration. The corrosion resistance of the Mg-Zn-Nd-Zr alloy P-type clip was better than that of the Mg-Zn-Nd alloy P-type clip (degradation rate of 2.02 mm/y and 2.61 mm/y on the 7th day, respectively). Mg-Zn-Nd-Zr alloy The P-type vascular clip remained closed even on the 7th day, which could meet the requirements of clinical application. |
| first_indexed | 2024-03-10T21:10:24Z |
| format | Article |
| id | doaj.art-fc5052be23b444f0b0cba82b815bf222 |
| institution | Directory Open Access Journal |
| issn | 2079-4983 |
| language | English |
| last_indexed | 2024-03-10T21:10:24Z |
| publishDate | 2023-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Functional Biomaterials |
| spelling | doaj.art-fc5052be23b444f0b0cba82b815bf2222023-11-19T16:55:37ZengMDPI AGJournal of Functional Biomaterials2079-49832023-10-01141050110.3390/jfb14100501Study on Mechanical Properties and Degradation Behavior of Magnesium Alloy Vascular ClipHongxu Zhang0Ming Gao1Xiaoying Tian2Dali Cao3Lili Tan4Materials Science and Engineering, Shenyang University of Chemical Technology, 11# Street Shenyang Economic & Technology Development Area, Shenyang 110142, ChinaInstitute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, ChinaInstitute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, ChinaMaterials Science and Engineering, Shenyang University of Chemical Technology, 11# Street Shenyang Economic & Technology Development Area, Shenyang 110142, ChinaInstitute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, ChinaThe Mg alloy vascular clip has biodegradability and good biocompatibility, which can improve the convenience and safety of clinical application. However, the Mg alloy vascular clip also has some disadvantages, such as an unreasonable structure design and a degradation rate which is too fast. In this study, the process of clamping blood vessels with a biodegradable Mg alloy (Mg-Zn-Nd-Zr and Mg-Zn-Nd) general V-type vascular clip was simulated by finite element simulation software (Abaqus). A new type of vascular clip, the P-type vascular clip, was analyzed and investigated through simulation. The differences between Mg alloy vascular clips of V-type and P-type were analyzed by finite element simulation. In addition, the effects of Zr element on the mechanical properties and corrosion resistance of P-type vascular clips were also investigated to improve the mechanical stability. The results show that during the V-type vascular clip closure of Mg-Zn-Nd-Zr alloy, this clip has some problems, such as uneven distribution of blood vessel stress, crevices in blood vessels and stress concentration. The improved P-type vascular clip has uniform closure, and there is no gap in the blood vessel, which can effectively avoid stress concentration. The improved P-type vascular clip is well closed and can effectively avoid stress concentration. The corrosion resistance of the Mg-Zn-Nd-Zr alloy P-type clip was better than that of the Mg-Zn-Nd alloy P-type clip (degradation rate of 2.02 mm/y and 2.61 mm/y on the 7th day, respectively). Mg-Zn-Nd-Zr alloy The P-type vascular clip remained closed even on the 7th day, which could meet the requirements of clinical application.https://www.mdpi.com/2079-4983/14/10/501finite element modellingbiodegradable Mg alloyvascular clipstructural designcorrosion resistance |
| spellingShingle | Hongxu Zhang Ming Gao Xiaoying Tian Dali Cao Lili Tan Study on Mechanical Properties and Degradation Behavior of Magnesium Alloy Vascular Clip Journal of Functional Biomaterials finite element modelling biodegradable Mg alloy vascular clip structural design corrosion resistance |
| title | Study on Mechanical Properties and Degradation Behavior of Magnesium Alloy Vascular Clip |
| title_full | Study on Mechanical Properties and Degradation Behavior of Magnesium Alloy Vascular Clip |
| title_fullStr | Study on Mechanical Properties and Degradation Behavior of Magnesium Alloy Vascular Clip |
| title_full_unstemmed | Study on Mechanical Properties and Degradation Behavior of Magnesium Alloy Vascular Clip |
| title_short | Study on Mechanical Properties and Degradation Behavior of Magnesium Alloy Vascular Clip |
| title_sort | study on mechanical properties and degradation behavior of magnesium alloy vascular clip |
| topic | finite element modelling biodegradable Mg alloy vascular clip structural design corrosion resistance |
| url | https://www.mdpi.com/2079-4983/14/10/501 |
| work_keys_str_mv | AT hongxuzhang studyonmechanicalpropertiesanddegradationbehaviorofmagnesiumalloyvascularclip AT minggao studyonmechanicalpropertiesanddegradationbehaviorofmagnesiumalloyvascularclip AT xiaoyingtian studyonmechanicalpropertiesanddegradationbehaviorofmagnesiumalloyvascularclip AT dalicao studyonmechanicalpropertiesanddegradationbehaviorofmagnesiumalloyvascularclip AT lilitan studyonmechanicalpropertiesanddegradationbehaviorofmagnesiumalloyvascularclip |