TROMBOCYTOSIS FOLLOWING SPLENECTOMY IN PEDIATRIC PATIENTS
Thrombocytosis represents a platelet count over 500.000/mm³. Objective. The aim of this study is to evaluate the frequency and gravity of reactive thrombocytosis in pediatric patients who underwent splenectomy. Material and method. We performed a retrospective study including 20 patients (4-16 yea...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Amaltea Medical Publishing House
2016-06-01
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| Series: | Romanian Journal of Pediatrics |
| Subjects: | |
| Online Access: | https://revistemedicale.amaltea.ro/Romanian_Journal_of_PEDIATRICS/Revista_Romana_de_PEDIATRIE-2016-Nr.2/RJP_2016_2_EN_Art-07.pdf |
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| author | Andreea Ligia Dinca Cristina Oana Marginean Despina Baghiu Alina Grama Horea Gozar Andreea Durlan Mihai Stanca Raluca Damian Mihaela Chincesan |
| author_facet | Andreea Ligia Dinca Cristina Oana Marginean Despina Baghiu Alina Grama Horea Gozar Andreea Durlan Mihai Stanca Raluca Damian Mihaela Chincesan |
| author_sort | Andreea Ligia Dinca |
| collection | DOAJ |
| description | Thrombocytosis represents a platelet count over 500.000/mm³.
Objective. The aim of this study is to evaluate the frequency and gravity of reactive thrombocytosis in pediatric patients who underwent splenectomy.
Material and method. We performed a retrospective study including 20 patients (4-16 years old) who underwent
splenectomy between 2006-2015. The inclusion criteria in the study were: patients with the age under 18 years,
who underwent splenectomy independently by the cause, and who developed afterwards thrombocytosis.
Results. In the studied group 64% of the splenectomised patients (16) developed a form of thrombocytosis. In
4 cases – severe form (Platelets > 1 million/mm3
) and in 7 cases a mild form. There were not noticed any significant differences regarding the gender repartition of the patients (9 were females, and 11 were males). In 13
patients, thrombocytosis disappeared after 30 days, and only in 3 cases, the episode lasted more than 360
days. Thrombotic phenomena were noticed only in one patient from our study group. All the patients benefited
from thromboprophylaxis and hydration measures, and 2 cases needed associated treatment with Hydroxyurea.
Conclusions. Our study reveals an increased frequency of thrombocytosis after splenectomy (80%), with a
maximum peak of incidence in 2-10 days following the intervention, thrombocytosis being generally benign and
self-limited; still one of the cases experienced thrombotic complications and severe thrombocytosis was more
frequent after post-traumatic splenectomy. |
| first_indexed | 2024-12-19T20:06:04Z |
| format | Article |
| id | doaj.art-fc528faee9e04de4983dfedf267b550d |
| institution | Directory Open Access Journal |
| issn | 1454-0398 2069-6175 |
| language | English |
| last_indexed | 2024-12-19T20:06:04Z |
| publishDate | 2016-06-01 |
| publisher | Amaltea Medical Publishing House |
| record_format | Article |
| series | Romanian Journal of Pediatrics |
| spelling | doaj.art-fc528faee9e04de4983dfedf267b550d2022-12-21T20:07:29ZengAmaltea Medical Publishing HouseRomanian Journal of Pediatrics1454-03982069-61752016-06-0165216616910.37897/RJP.2016.2.7TROMBOCYTOSIS FOLLOWING SPLENECTOMY IN PEDIATRIC PATIENTSAndreea Ligia Dinca0Cristina Oana Marginean1Despina Baghiu2Alina Grama3Horea Gozar4Andreea Durlan5Mihai Stanca6Raluca Damian7Mihaela Chincesan8Pediatrics Clinic I, University of Medicine and Pharmacy, Targu-MuresPediatrics Clinic I, University of Medicine and Pharmacy, Targu-MuresPediatrics Clinic I, University of Medicine and Pharmacy, Targu-MuresPediatrics Clinic I, University of Medicine and Pharmacy, Targu-MuresPediatrics Surgery and Orthopedic Clinic, University of Medicine and Pharmacy, Targu-MuresPediatrics Clinic I, University of Medicine and Pharmacy, Targu-MuresUniversity of Medicine and Pharmacy, Targu-MuresNeonatology Clinic I, Emergency Clinical County Hospital of Targu-MuresPediatrics Clinic I, University of Medicine and Pharmacy, Targu-MuresThrombocytosis represents a platelet count over 500.000/mm³. Objective. The aim of this study is to evaluate the frequency and gravity of reactive thrombocytosis in pediatric patients who underwent splenectomy. Material and method. We performed a retrospective study including 20 patients (4-16 years old) who underwent splenectomy between 2006-2015. The inclusion criteria in the study were: patients with the age under 18 years, who underwent splenectomy independently by the cause, and who developed afterwards thrombocytosis. Results. In the studied group 64% of the splenectomised patients (16) developed a form of thrombocytosis. In 4 cases – severe form (Platelets > 1 million/mm3 ) and in 7 cases a mild form. There were not noticed any significant differences regarding the gender repartition of the patients (9 were females, and 11 were males). In 13 patients, thrombocytosis disappeared after 30 days, and only in 3 cases, the episode lasted more than 360 days. Thrombotic phenomena were noticed only in one patient from our study group. All the patients benefited from thromboprophylaxis and hydration measures, and 2 cases needed associated treatment with Hydroxyurea. Conclusions. Our study reveals an increased frequency of thrombocytosis after splenectomy (80%), with a maximum peak of incidence in 2-10 days following the intervention, thrombocytosis being generally benign and self-limited; still one of the cases experienced thrombotic complications and severe thrombocytosis was more frequent after post-traumatic splenectomy.https://revistemedicale.amaltea.ro/Romanian_Journal_of_PEDIATRICS/Revista_Romana_de_PEDIATRIE-2016-Nr.2/RJP_2016_2_EN_Art-07.pdfthrombocytosissplenectomychild |
| spellingShingle | Andreea Ligia Dinca Cristina Oana Marginean Despina Baghiu Alina Grama Horea Gozar Andreea Durlan Mihai Stanca Raluca Damian Mihaela Chincesan TROMBOCYTOSIS FOLLOWING SPLENECTOMY IN PEDIATRIC PATIENTS Romanian Journal of Pediatrics thrombocytosis splenectomy child |
| title | TROMBOCYTOSIS FOLLOWING SPLENECTOMY IN PEDIATRIC PATIENTS |
| title_full | TROMBOCYTOSIS FOLLOWING SPLENECTOMY IN PEDIATRIC PATIENTS |
| title_fullStr | TROMBOCYTOSIS FOLLOWING SPLENECTOMY IN PEDIATRIC PATIENTS |
| title_full_unstemmed | TROMBOCYTOSIS FOLLOWING SPLENECTOMY IN PEDIATRIC PATIENTS |
| title_short | TROMBOCYTOSIS FOLLOWING SPLENECTOMY IN PEDIATRIC PATIENTS |
| title_sort | trombocytosis following splenectomy in pediatric patients |
| topic | thrombocytosis splenectomy child |
| url | https://revistemedicale.amaltea.ro/Romanian_Journal_of_PEDIATRICS/Revista_Romana_de_PEDIATRIE-2016-Nr.2/RJP_2016_2_EN_Art-07.pdf |
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