Enhanced Bioavailability of AC1497, a Novel Anticancer Drug Candidate, via a Self-Nanoemulsifying Drug Delivery System
AC1497 is an effective dual inhibitor of malate dehydrogenase 1 and 2 targeting cancer metabolism. However, its poor aqueous solubility results in low bioavailability, limiting its clinical development. This study was conducted to develop an effective self-nanoemulsifying drug delivery system (SNEDD...
| Main Authors: | , , , , , , , |
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| פורמט: | Article |
| שפה: | English |
| יצא לאור: |
MDPI AG
2021-07-01
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| סדרה: | Pharmaceutics |
| נושאים: | |
| גישה מקוונת: | https://www.mdpi.com/1999-4923/13/8/1142 |