Enhanced Bioavailability of AC1497, a Novel Anticancer Drug Candidate, via a Self-Nanoemulsifying Drug Delivery System

Enhanced Bioavailability of AC1497, a Novel Anticancer Drug Candidate, via a Self-Nanoemulsifying Drug Delivery System

AC1497 is an effective dual inhibitor of malate dehydrogenase 1 and 2 targeting cancer metabolism. However, its poor aqueous solubility results in low bioavailability, limiting its clinical development. This study was conducted to develop an effective self-nanoemulsifying drug delivery system (SNEDD...

Bibliográfalaš dieđut
Váldodahkkit:	Kshitis Chandra Baral, Jae-Geun Song, Sang Hoon Lee, Rajiv Bajracharya, Godesi Sreenivasulu, Minkyoung Kim, Kyeong Lee, Hyo-Kyung Han
Materiálatiipa:	Artihkal
Giella:	English
Almmustuhtton:	MDPI AG 2021-07-01
Ráidu:	Pharmaceutics
Fáttát:	AC1497 self-nanoemulsifying drug delivery system bioavailability dissolution solubilization
Liŋkkat:	https://www.mdpi.com/1999-4923/13/8/1142

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