Exploring Peruvian Cocoa Populations and Their Influence on Rat Metabolism
This study aimed to characterize two Peruvian cocoa populations (CCN51 and JL2) and determine their influence on rat metabolism. For this, the phytochemical composition and in vitro antioxidant activity of CCN51 and JL2 were established. Furthermore, Wistar rats were fed with either CCN51-, JL2-enri...
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| Format: | Article |
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MDPI AG
2023-11-01
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| Series: | Biology and Life Sciences Forum |
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| Online Access: | https://www.mdpi.com/2673-9976/29/1/8 |
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| author | Malén Massot-Cladera Raquel García-Valdera Daniela Gálvez-González María J. Rodríguez-Lagunas Francisco J. Pérez-Cano Ivan Best Margarida Castell |
| author_facet | Malén Massot-Cladera Raquel García-Valdera Daniela Gálvez-González María J. Rodríguez-Lagunas Francisco J. Pérez-Cano Ivan Best Margarida Castell |
| author_sort | Malén Massot-Cladera |
| collection | DOAJ |
| description | This study aimed to characterize two Peruvian cocoa populations (CCN51 and JL2) and determine their influence on rat metabolism. For this, the phytochemical composition and in vitro antioxidant activity of CCN51 and JL2 were established. Furthermore, Wistar rats were fed with either CCN51-, JL2-enriched or standard diets for 4 weeks. At the end, an oral glucose tolerance test was carried out. Moreover, visceral adiposity index and fecal pH were measured. The JL2 cocoa showed the highest content of total polyphenols, catechin and epigallocatechin-3-gallate as well as the highest in vitro antioxidant activity. No significant differences were observed in glycemia among the three experimental groups, but both cocoa-fed groups showed lower visceral adiposity than the standard diet-fed animals. Lower fecal pH was observed after both cocoa diets. In conclusion, two Peruvian cocoa populations with different polyphenol compositions induced similar effects on rat metabolism when administered as 10% of the diet for 4 weeks. |
| first_indexed | 2024-04-24T18:29:40Z |
| format | Article |
| id | doaj.art-fc54f0920247498aa6cb5dc4b53ac296 |
| institution | Directory Open Access Journal |
| issn | 2673-9976 |
| language | English |
| last_indexed | 2024-04-24T18:29:40Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biology and Life Sciences Forum |
| spelling | doaj.art-fc54f0920247498aa6cb5dc4b53ac2962024-03-27T13:28:32ZengMDPI AGBiology and Life Sciences Forum2673-99762023-11-01291810.3390/IECN2023-15792Exploring Peruvian Cocoa Populations and Their Influence on Rat MetabolismMalén Massot-Cladera0Raquel García-Valdera1Daniela Gálvez-González2María J. Rodríguez-Lagunas3Francisco J. Pérez-Cano4Ivan Best5Margarida Castell6Section of Physiology, Department of Biochemistry and Physiology, Faculty of Pharmacy and Food Science, University of Barcelona (UB), 08028 Barcelona, SpainFacultad de Ingeniería, Universidad San Ignacio de Loyola (USIL), Lima 15024, PeruFacultad de Ingeniería, Universidad San Ignacio de Loyola (USIL), Lima 15024, PeruSection of Physiology, Department of Biochemistry and Physiology, Faculty of Pharmacy and Food Science, University of Barcelona (UB), 08028 Barcelona, SpainSection of Physiology, Department of Biochemistry and Physiology, Faculty of Pharmacy and Food Science, University of Barcelona (UB), 08028 Barcelona, SpainInstituto de Ciencias de los Alimentos y Nutrición, Universidad San Ignacio de Loyola (USIL), Lima 15024, PeruSection of Physiology, Department of Biochemistry and Physiology, Faculty of Pharmacy and Food Science, University of Barcelona (UB), 08028 Barcelona, SpainThis study aimed to characterize two Peruvian cocoa populations (CCN51 and JL2) and determine their influence on rat metabolism. For this, the phytochemical composition and in vitro antioxidant activity of CCN51 and JL2 were established. Furthermore, Wistar rats were fed with either CCN51-, JL2-enriched or standard diets for 4 weeks. At the end, an oral glucose tolerance test was carried out. Moreover, visceral adiposity index and fecal pH were measured. The JL2 cocoa showed the highest content of total polyphenols, catechin and epigallocatechin-3-gallate as well as the highest in vitro antioxidant activity. No significant differences were observed in glycemia among the three experimental groups, but both cocoa-fed groups showed lower visceral adiposity than the standard diet-fed animals. Lower fecal pH was observed after both cocoa diets. In conclusion, two Peruvian cocoa populations with different polyphenol compositions induced similar effects on rat metabolism when administered as 10% of the diet for 4 weeks.https://www.mdpi.com/2673-9976/29/1/8<i>Theobroma cacao</i>polyphenolsmetabolism |
| spellingShingle | Malén Massot-Cladera Raquel García-Valdera Daniela Gálvez-González María J. Rodríguez-Lagunas Francisco J. Pérez-Cano Ivan Best Margarida Castell Exploring Peruvian Cocoa Populations and Their Influence on Rat Metabolism Biology and Life Sciences Forum <i>Theobroma cacao</i> polyphenols metabolism |
| title | Exploring Peruvian Cocoa Populations and Their Influence on Rat Metabolism |
| title_full | Exploring Peruvian Cocoa Populations and Their Influence on Rat Metabolism |
| title_fullStr | Exploring Peruvian Cocoa Populations and Their Influence on Rat Metabolism |
| title_full_unstemmed | Exploring Peruvian Cocoa Populations and Their Influence on Rat Metabolism |
| title_short | Exploring Peruvian Cocoa Populations and Their Influence on Rat Metabolism |
| title_sort | exploring peruvian cocoa populations and their influence on rat metabolism |
| topic | <i>Theobroma cacao</i> polyphenols metabolism |
| url | https://www.mdpi.com/2673-9976/29/1/8 |
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