T cells and macrophages responding to oxidative damage cooperate in pathogenesis of a mouse model of age-related macular degeneration.

T cells and macrophages responding to oxidative damage cooperate in pathogenesis of a mouse model of age-related macular degeneration.

Age-related macular degeneration (AMD) is a major disease affecting central vision, but the pathogenic mechanisms are not fully understood. Using a mouse model, we examined the relationship of two factors implicated in AMD development: oxidative stress and the immune system. Carboxyethylpyrrole (CEP...

Full description

Bibliographic Details
Main Authors: Fernando Cruz-Guilloty, Ali M Saeed, Stephanie Duffort, Marisol Cano, Katayoon B Ebrahimi, Asha Ballmick, Yaohong Tan, Hua Wang, James M Laird, Robert G Salomon, James T Handa, Victor L Perez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3929609?pdf=render

Similar Items

Similar Items