Effects of air pollution on adverse birth outcomes and pregnancy complications in the U.S. state of Kansas (2000–2015)
Abstract Neonatal mortality and morbidity are often caused by preterm birth and lower birth weight. Gestational diabetes mellitus (GDM) and gestational hypertension (GH) are the most prevalent maternal medical complications during pregnancy. However, evidence on effects of air pollution on adverse b...
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| Format: | Article |
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Nature Portfolio
2023-12-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-48329-5 |
| _version_ | 1797398050862268416 |
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| author | Hua Hao Sodahm R. Yoo Matthew J. Strickland Lyndsey A. Darrow Rohan R. D’Souza Joshua L. Warren Shannon Moss Huaqing Wang Haisu Zhang Howard H. Chang |
| author_facet | Hua Hao Sodahm R. Yoo Matthew J. Strickland Lyndsey A. Darrow Rohan R. D’Souza Joshua L. Warren Shannon Moss Huaqing Wang Haisu Zhang Howard H. Chang |
| author_sort | Hua Hao |
| collection | DOAJ |
| description | Abstract Neonatal mortality and morbidity are often caused by preterm birth and lower birth weight. Gestational diabetes mellitus (GDM) and gestational hypertension (GH) are the most prevalent maternal medical complications during pregnancy. However, evidence on effects of air pollution on adverse birth outcomes and pregnancy complications is mixed. Singleton live births conceived between January 1st, 2000, and December 31st, 2015, and reached at least 27 weeks of pregnancy in Kansas were included in the study. Trimester-specific and total pregnancy exposures to nitrogen dioxide (NO2), particulate matter with an aerodynamic diameter less than 2.5 μm (PM2.5), and ozone (O3) were estimated using spatiotemporal ensemble models and assigned to maternal residential census tracts. Logistic regression, discrete-time survival, and linear models were applied to assess the associations. After adjustment for demographics and socio-economic status (SES) factors, we found increases in the second and third trimesters and total pregnancy O3 exposures were significantly linked to preterm birth. Exposure to the second and third trimesters O3 was significantly associated with lower birth weight, and exposure to NO2 during the first trimester was linked to an increased risk of GDM. O3 exposures in the first trimester were connected to an elevated risk of GH. We didn’t observe consistent associations between adverse pregnancy and birth outcomes with PM2.5 exposure. Our findings indicate there is a positive link between increased O3 exposure during pregnancy and a higher risk of preterm birth, GH, and decreased birth weight. Our work supports limiting population exposure to air pollution, which may lower the likelihood of adverse birth and pregnancy outcomes. |
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| format | Article |
| id | doaj.art-fc582864b9c7429c8b9a0c79b24379a1 |
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| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-09T01:20:06Z |
| publishDate | 2023-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-fc582864b9c7429c8b9a0c79b24379a12023-12-10T12:15:53ZengNature PortfolioScientific Reports2045-23222023-12-0113111010.1038/s41598-023-48329-5Effects of air pollution on adverse birth outcomes and pregnancy complications in the U.S. state of Kansas (2000–2015)Hua Hao0Sodahm R. Yoo1Matthew J. Strickland2Lyndsey A. Darrow3Rohan R. D’Souza4Joshua L. Warren5Shannon Moss6Huaqing Wang7Haisu Zhang8Howard H. Chang9Gangarosa Department of Environmental Health, Rollins School of Public Health, Emory UniversityDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory UniversityDepatment of Health Analytics and Biostatistics, Epidemiology and Environmental Health, School of Public Health, University of NevadaDepatment of Health Analytics and Biostatistics, Epidemiology and Environmental Health, School of Public Health, University of NevadaDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory UniversityDepartment of Biostatistics, School of Medicine, Yale UniversityDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory UniversityDepartment of Landscape Architecture and Environment Planning, College of Agriculture and Applied Sciences, Utah State UniversityGangarosa Department of Environmental Health, Rollins School of Public Health, Emory UniversityGangarosa Department of Environmental Health, Rollins School of Public Health, Emory UniversityAbstract Neonatal mortality and morbidity are often caused by preterm birth and lower birth weight. Gestational diabetes mellitus (GDM) and gestational hypertension (GH) are the most prevalent maternal medical complications during pregnancy. However, evidence on effects of air pollution on adverse birth outcomes and pregnancy complications is mixed. Singleton live births conceived between January 1st, 2000, and December 31st, 2015, and reached at least 27 weeks of pregnancy in Kansas were included in the study. Trimester-specific and total pregnancy exposures to nitrogen dioxide (NO2), particulate matter with an aerodynamic diameter less than 2.5 μm (PM2.5), and ozone (O3) were estimated using spatiotemporal ensemble models and assigned to maternal residential census tracts. Logistic regression, discrete-time survival, and linear models were applied to assess the associations. After adjustment for demographics and socio-economic status (SES) factors, we found increases in the second and third trimesters and total pregnancy O3 exposures were significantly linked to preterm birth. Exposure to the second and third trimesters O3 was significantly associated with lower birth weight, and exposure to NO2 during the first trimester was linked to an increased risk of GDM. O3 exposures in the first trimester were connected to an elevated risk of GH. We didn’t observe consistent associations between adverse pregnancy and birth outcomes with PM2.5 exposure. Our findings indicate there is a positive link between increased O3 exposure during pregnancy and a higher risk of preterm birth, GH, and decreased birth weight. Our work supports limiting population exposure to air pollution, which may lower the likelihood of adverse birth and pregnancy outcomes.https://doi.org/10.1038/s41598-023-48329-5 |
| spellingShingle | Hua Hao Sodahm R. Yoo Matthew J. Strickland Lyndsey A. Darrow Rohan R. D’Souza Joshua L. Warren Shannon Moss Huaqing Wang Haisu Zhang Howard H. Chang Effects of air pollution on adverse birth outcomes and pregnancy complications in the U.S. state of Kansas (2000–2015) Scientific Reports |
| title | Effects of air pollution on adverse birth outcomes and pregnancy complications in the U.S. state of Kansas (2000–2015) |
| title_full | Effects of air pollution on adverse birth outcomes and pregnancy complications in the U.S. state of Kansas (2000–2015) |
| title_fullStr | Effects of air pollution on adverse birth outcomes and pregnancy complications in the U.S. state of Kansas (2000–2015) |
| title_full_unstemmed | Effects of air pollution on adverse birth outcomes and pregnancy complications in the U.S. state of Kansas (2000–2015) |
| title_short | Effects of air pollution on adverse birth outcomes and pregnancy complications in the U.S. state of Kansas (2000–2015) |
| title_sort | effects of air pollution on adverse birth outcomes and pregnancy complications in the u s state of kansas 2000 2015 |
| url | https://doi.org/10.1038/s41598-023-48329-5 |
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