Ivermectin-induced gene expression changes in adult Parascaris univalens and Caenorhabditis elegans: a comparative approach to study anthelminthic metabolism and resistance in vitro

Ivermectin-induced gene expression changes in adult Parascaris univalens and Caenorhabditis elegans: a comparative approach to study anthelminthic metabolism and resistance in vitro

Abstract Background The nematode Parascaris univalens is one of the most prevalent parasitic pathogens infecting horses but anthelmintic resistance undermines treatment approaches. The molecular mechanisms underlying drug activity and resistance remain poorly understood in this parasite since experi...

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Bibliographic Details
Main Authors: Faruk Dube, Andrea Hinas, Shweta Roy, Frida Martin, Magnus Åbrink, Staffan Svärd, Eva Tydén
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Parasites & Vectors
Subjects:
Equine roundworm
Gene expression
Anthelmintic resistance
RNA sequencing
Online Access:https://doi.org/10.1186/s13071-022-05260-4

Internet

https://doi.org/10.1186/s13071-022-05260-4

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