Asthma changes at a Pediatric Intensive Care Unit after 10 years: Observational study
Objectives: To describe the change in the management, and outcome of children with acute severe asthma (ASA) admitted to Pediatric Intensive Care Unit (PICU) at tertiary institute, as compared to previously published report in 2003. Methods : This is a retrospective observational study. All consecu...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | Annals of Thoracic Medicine |
| Subjects: | |
| Online Access: | http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2015;volume=10;issue=4;spage=243;epage=248;aulast=Al-Eyadhy |
| _version_ | 1819231168445284352 |
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| author | Ayman A Al-Eyadhy Mohamad-Hani Temsah Ali A. N. Alhaboob Abdulmalik K Aldubayan Nasser A Almousa Abdulrahman M Alsharidah Mohammed I Alangari Abdulrahman M Alshaya |
| author_facet | Ayman A Al-Eyadhy Mohamad-Hani Temsah Ali A. N. Alhaboob Abdulmalik K Aldubayan Nasser A Almousa Abdulrahman M Alsharidah Mohammed I Alangari Abdulrahman M Alshaya |
| author_sort | Ayman A Al-Eyadhy |
| collection | DOAJ |
| description | Objectives: To describe the change in the management, and outcome of children with acute severe asthma (ASA) admitted to Pediatric Intensive Care Unit (PICU) at tertiary institute, as compared to previously published report in 2003.
Methods : This is a retrospective observational study. All consecutive pediatric ASA patients who were admitted to PICU during the study period were included. The data were extracted from PICU database and medical records. The Cohort in this study (2013 Cohort) was compared with the Cohort of ASA, which was published in 2003 from the same institution (2003 Cohort).
Results: In comparison to previous 2003 Cohort, current Cohort (2013) revealed higher mean age (5.5 vs. 3.6 years; P ≤ 0.001), higher rate of PICU admission (20.3% vs. 3.6%; P ≤ 0.007), less patients who received maintenance inhaled steroids (43.3% vs. 62.4%; P ≤ 0.03), less patients with pH <7.3 (17.9% vs. 42.9%; P ≤ 0.001). There were more patients in 2013 Cohort who received: Inhaled Ipratropium bromide (97% vs. 68%; P ≤ 0.001), intravenous magnesium sulfate (68.2% vs. none), intravenous salbutamol (13.6% vs. 3.6%; P ≤ 0.015), and noninvasive ventilation (NIV) (35.8% vs. none) while no patients were treated with theophylline (none vs. 62.5%). The median length of stay (LOS) was 2 days while mean LOS was half a day longer in the 2013 Cohort. None of our patients required intubation, and there was no mortality.
Conclusion: We observed slight shift toward older age, considerably increased the rate of PICU admission, increased utilization of Ipratropium bromide, magnesium sulfate, and NIV as important modalities of treatment. |
| first_indexed | 2024-12-23T11:40:40Z |
| format | Article |
| id | doaj.art-fc5ab41b23ed4734b48d5728f7eb2d79 |
| institution | Directory Open Access Journal |
| issn | 1817-1737 1998-3557 |
| language | English |
| last_indexed | 2024-12-23T11:40:40Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Thoracic Medicine |
| spelling | doaj.art-fc5ab41b23ed4734b48d5728f7eb2d792022-12-21T17:48:29ZengWolters Kluwer Medknow PublicationsAnnals of Thoracic Medicine1817-17371998-35572015-01-0110424324810.4103/1817-1737.165302Asthma changes at a Pediatric Intensive Care Unit after 10 years: Observational studyAyman A Al-EyadhyMohamad-Hani TemsahAli A. N. AlhaboobAbdulmalik K AldubayanNasser A AlmousaAbdulrahman M AlsharidahMohammed I AlangariAbdulrahman M AlshayaObjectives: To describe the change in the management, and outcome of children with acute severe asthma (ASA) admitted to Pediatric Intensive Care Unit (PICU) at tertiary institute, as compared to previously published report in 2003. Methods : This is a retrospective observational study. All consecutive pediatric ASA patients who were admitted to PICU during the study period were included. The data were extracted from PICU database and medical records. The Cohort in this study (2013 Cohort) was compared with the Cohort of ASA, which was published in 2003 from the same institution (2003 Cohort). Results: In comparison to previous 2003 Cohort, current Cohort (2013) revealed higher mean age (5.5 vs. 3.6 years; P ≤ 0.001), higher rate of PICU admission (20.3% vs. 3.6%; P ≤ 0.007), less patients who received maintenance inhaled steroids (43.3% vs. 62.4%; P ≤ 0.03), less patients with pH <7.3 (17.9% vs. 42.9%; P ≤ 0.001). There were more patients in 2013 Cohort who received: Inhaled Ipratropium bromide (97% vs. 68%; P ≤ 0.001), intravenous magnesium sulfate (68.2% vs. none), intravenous salbutamol (13.6% vs. 3.6%; P ≤ 0.015), and noninvasive ventilation (NIV) (35.8% vs. none) while no patients were treated with theophylline (none vs. 62.5%). The median length of stay (LOS) was 2 days while mean LOS was half a day longer in the 2013 Cohort. None of our patients required intubation, and there was no mortality. Conclusion: We observed slight shift toward older age, considerably increased the rate of PICU admission, increased utilization of Ipratropium bromide, magnesium sulfate, and NIV as important modalities of treatment.http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2015;volume=10;issue=4;spage=243;epage=248;aulast=Al-EyadhyAsthmachildrencritical careepidemiologynoninvasive ventilationpediatricSaudistatus asthmaticus |
| spellingShingle | Ayman A Al-Eyadhy Mohamad-Hani Temsah Ali A. N. Alhaboob Abdulmalik K Aldubayan Nasser A Almousa Abdulrahman M Alsharidah Mohammed I Alangari Abdulrahman M Alshaya Asthma changes at a Pediatric Intensive Care Unit after 10 years: Observational study Annals of Thoracic Medicine Asthma children critical care epidemiology noninvasive ventilation pediatric Saudi status asthmaticus |
| title | Asthma changes at a Pediatric Intensive Care Unit after 10 years: Observational study |
| title_full | Asthma changes at a Pediatric Intensive Care Unit after 10 years: Observational study |
| title_fullStr | Asthma changes at a Pediatric Intensive Care Unit after 10 years: Observational study |
| title_full_unstemmed | Asthma changes at a Pediatric Intensive Care Unit after 10 years: Observational study |
| title_short | Asthma changes at a Pediatric Intensive Care Unit after 10 years: Observational study |
| title_sort | asthma changes at a pediatric intensive care unit after 10 years observational study |
| topic | Asthma children critical care epidemiology noninvasive ventilation pediatric Saudi status asthmaticus |
| url | http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2015;volume=10;issue=4;spage=243;epage=248;aulast=Al-Eyadhy |
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