The Interaction Between lncRNA SNHG6 and hnRNPA1 Contributes to the Growth of Colorectal Cancer by Enhancing Aerobic Glycolysis Through the Regulation of Alternative Splicing of PKM

The Interaction Between lncRNA SNHG6 and hnRNPA1 Contributes to the Growth of Colorectal Cancer by Enhancing Aerobic Glycolysis Through the Regulation of Alternative Splicing of PKM

Background: Small nucleolar RNA host gene 6 (SNHG6) acts as a carcinogenic gene in colorectal cancer (CRC). However, previous studies on the mechanism by which long non-coding RNA (lncRNA) SNHG6 exerts its carcinogenic effect in CRC have not involved the direct interaction between SNHG6 and proteins...

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Bibliographic Details
Main Authors: Zhixian Lan, Xiang Yao, Kangyue Sun, Aimin Li, Side Liu, Xinke Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Oncology
Subjects:
colorectal cancer
small nucleolar RNA host gene 6
comprehensive RNA-binding proteins–mass spectrometry
bioinformatics analysis
heterogeneous nuclear ribonucleoprotein A1
pyruvate kinase M
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00363/full

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