Pan-Cancer Analysis of Alternative Lengthening of Telomere Activity

Pan-Cancer Analysis of Alternative Lengthening of Telomere Activity

Alternative lengthening of telomeres (ALT) is a telomerase-independent mechanism that extends telomeres in cancer cells. It influences tumorigenesis and patient survival. Despite the clinical significance of ALT in tumors, the manner in which ALT is activated and influences prognostic outcomes in di...

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Bibliographic Details
Main Authors: Ji-Yong Sung, Hee-Woong Lim, Je-Gun Joung, Woong-Yang Park
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cancers
Subjects:
telomere maintenance mechanism
alternative lengthening of telomeres
cancers
gene expression
survival analysis
Online Access:https://www.mdpi.com/2072-6694/12/8/2207

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