Risk factors and foetal growth restriction associated with expectant treatment of early-onset preeclampsia
Objective To identify the factors affecting expectant management of early-onset preeclampsia, and evaluate the correlation between expectant treatment and foetal growth restriction.Materials and Methods The retrospective study included 72 women who were admitted for early-onset preeclampsia between...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-12-01
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| Series: | Annals of Medicine |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/07853890.2022.2144642 |
| _version_ | 1811226051514204160 |
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| author | Jiao Yi Lei Chen Xianglian Meng Yi Chen |
| author_facet | Jiao Yi Lei Chen Xianglian Meng Yi Chen |
| author_sort | Jiao Yi |
| collection | DOAJ |
| description | Objective To identify the factors affecting expectant management of early-onset preeclampsia, and evaluate the correlation between expectant treatment and foetal growth restriction.Materials and Methods The retrospective study included 72 women who were admitted for early-onset preeclampsia between February 2018 to April 2021. Data included maternal clinical parameters, demographic and maternal and neonatal outcomes, which were analysed for correlation.Results Multiple logistic regression analysis demonstrated that the time interval from the onset of 24-h proteinuria to termination of pregnancy showed a strong correlation with the expectant treatment; Univariate logistic analysis confirmed that there was no correlation between expectant treatment and foetal growth restriction.Conclusion There was a negative correlation between the duration of 24-h proteinuria and the expectant treatment of patients with early-onset preeclampsia; Expectant treatment could not improve the development of foetal growth restriction in patients with early-onset preeclampsia.KEY MESSAGESThe duration of 24-h proteinuria affects the effectiveness of expectant management of early-onset preeclampsia.Expectant management can reduce adverse neonatal outcomes due to iatrogenic preterm delivery, but it cannot improve the occurrence of foetal growth restriction. |
| first_indexed | 2024-04-12T09:17:48Z |
| format | Article |
| id | doaj.art-fc5edb569dfc484b98d5e16248417bca |
| institution | Directory Open Access Journal |
| issn | 0785-3890 1365-2060 |
| language | English |
| last_indexed | 2024-04-12T09:17:48Z |
| publishDate | 2022-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Annals of Medicine |
| spelling | doaj.art-fc5edb569dfc484b98d5e16248417bca2022-12-22T03:38:47ZengTaylor & Francis GroupAnnals of Medicine0785-38901365-20602022-12-015413250325710.1080/07853890.2022.2144642Risk factors and foetal growth restriction associated with expectant treatment of early-onset preeclampsiaJiao Yi0Lei Chen1Xianglian Meng2Yi Chen3Department of Obstetrics and Gynecology, Maternal and Child Health Care Hospital Affiliated with Anhui Medical University, Anhui Maternal and Child Health Care Hospital, Hefei, ChinaDepartment of Obstetrics and Gynecology, Maternal and Child Health Care Hospital Affiliated with Anhui Medical University, Anhui Maternal and Child Health Care Hospital, Hefei, ChinaDepartment of Obstetrics and Gynecology, Maternal and Child Health Care Hospital Affiliated with Anhui Medical University, Anhui Maternal and Child Health Care Hospital, Hefei, ChinaDepartment of Obstetrics and Gynecology, Maternal and Child Health Care Hospital Affiliated with Anhui Medical University, Anhui Maternal and Child Health Care Hospital, Hefei, ChinaObjective To identify the factors affecting expectant management of early-onset preeclampsia, and evaluate the correlation between expectant treatment and foetal growth restriction.Materials and Methods The retrospective study included 72 women who were admitted for early-onset preeclampsia between February 2018 to April 2021. Data included maternal clinical parameters, demographic and maternal and neonatal outcomes, which were analysed for correlation.Results Multiple logistic regression analysis demonstrated that the time interval from the onset of 24-h proteinuria to termination of pregnancy showed a strong correlation with the expectant treatment; Univariate logistic analysis confirmed that there was no correlation between expectant treatment and foetal growth restriction.Conclusion There was a negative correlation between the duration of 24-h proteinuria and the expectant treatment of patients with early-onset preeclampsia; Expectant treatment could not improve the development of foetal growth restriction in patients with early-onset preeclampsia.KEY MESSAGESThe duration of 24-h proteinuria affects the effectiveness of expectant management of early-onset preeclampsia.Expectant management can reduce adverse neonatal outcomes due to iatrogenic preterm delivery, but it cannot improve the occurrence of foetal growth restriction.https://www.tandfonline.com/doi/10.1080/07853890.2022.2144642Preeclampsiaearly onset preeclampsiafoetal growth restrictionexpectant treatment24-h proteinuria |
| spellingShingle | Jiao Yi Lei Chen Xianglian Meng Yi Chen Risk factors and foetal growth restriction associated with expectant treatment of early-onset preeclampsia Annals of Medicine Preeclampsia early onset preeclampsia foetal growth restriction expectant treatment 24-h proteinuria |
| title | Risk factors and foetal growth restriction associated with expectant treatment of early-onset preeclampsia |
| title_full | Risk factors and foetal growth restriction associated with expectant treatment of early-onset preeclampsia |
| title_fullStr | Risk factors and foetal growth restriction associated with expectant treatment of early-onset preeclampsia |
| title_full_unstemmed | Risk factors and foetal growth restriction associated with expectant treatment of early-onset preeclampsia |
| title_short | Risk factors and foetal growth restriction associated with expectant treatment of early-onset preeclampsia |
| title_sort | risk factors and foetal growth restriction associated with expectant treatment of early onset preeclampsia |
| topic | Preeclampsia early onset preeclampsia foetal growth restriction expectant treatment 24-h proteinuria |
| url | https://www.tandfonline.com/doi/10.1080/07853890.2022.2144642 |
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