Targeting the Hedgehog Pathway in Cancer: Current Evidence and Future Perspectives

Targeting the Hedgehog Pathway in Cancer: Current Evidence and Future Perspectives

The Hedgehog pathway (HhP) plays an important role in normal embryonic development and its abnormal function has been linked to a variety of neoplasms. Recently, the complex mechanisms involved in this pathway have been deciphered and the cross talks with other important pathways involved in carcino...

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Bibliographic Details
Main Authors: Daniel Girardi, Adriana Barrichello, Gustavo Fernandes, Allan Pereira
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Cells
Subjects:
Hedgehog
targeted therapy
SMO inhibitor
GLI
Online Access:https://www.mdpi.com/2073-4409/8/2/153

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