Oncolytic Adenovirus-Loaded Menstrual Blood Stem Cells Overcome the Blockade of Viral Activity Exerted by Ovarian Cancer Ascites

Oncolytic Adenovirus-Loaded Menstrual Blood Stem Cells Overcome the Blockade of Viral Activity Exerted by Ovarian Cancer Ascites

Patients with ovarian cancer present peritoneal ascites at recurrence as a marker of disseminated disease and dismal prognosis. Oncolytic immunotherapy is an emerging approach for the treatment of disseminated cancer. In the present work, we constructed a novel oncolytic adenovirus, AR2011, to targe...

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Bibliographic Details
Main Authors: Ana Laura Alfano, Alejandro Nicola Candia, Nicasio Cuneo, Leandro N. Guttlein, Alejandro Soderini, Cecilia Rotondaro, Leonardo Sganga, Osvaldo L. Podhajcer, M. Veronica Lopez
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Molecular Therapy: Oncolytics
Subjects:
CRAd
ovarian cancer
MSC
peritoneal carcinosis
Online Access:http://www.sciencedirect.com/science/article/pii/S237277051730027X

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