Pulmonary artery vasodilators for treatment of pulmonary hypertension complicating fibrosing mediastinitis
Fibrosing mediastinitis (FM) is a heterogeneous disease characterized by sclerosing fibrosis of mediastinal structures. Pulmonary hypertension (PH) may complicate the course of the disease and can contribute significantly to the morbidity of FM. Due to the rarity and complexity of the disease, evide...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | Respiratory Medicine Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007124000297 |
| _version_ | 1797248384739835904 |
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| author | Daniel Van Kalsbeek Abedel Rahman Anani Karim El-Kersh |
| author_facet | Daniel Van Kalsbeek Abedel Rahman Anani Karim El-Kersh |
| author_sort | Daniel Van Kalsbeek |
| collection | DOAJ |
| description | Fibrosing mediastinitis (FM) is a heterogeneous disease characterized by sclerosing fibrosis of mediastinal structures. Pulmonary hypertension (PH) may complicate the course of the disease and can contribute significantly to the morbidity of FM. Due to the rarity and complexity of the disease, evidence-based guidelines are not currently available, and the optimal treatment approach is unknown. Management approaches should be individualized, and current techniques are often unsatisfactory. Here, we present two cases of PH complicating FM that were managed using pulmonary artery vasodilator therapy with excellent hemodynamic response. |
| first_indexed | 2024-04-24T20:13:44Z |
| format | Article |
| id | doaj.art-fc68d1ea651f4e60a868319acf282192 |
| institution | Directory Open Access Journal |
| issn | 2213-0071 |
| language | English |
| last_indexed | 2024-04-24T20:13:44Z |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Respiratory Medicine Case Reports |
| spelling | doaj.art-fc68d1ea651f4e60a868319acf2821922024-03-23T06:24:10ZengElsevierRespiratory Medicine Case Reports2213-00712024-01-0149102006Pulmonary artery vasodilators for treatment of pulmonary hypertension complicating fibrosing mediastinitisDaniel Van Kalsbeek0Abedel Rahman Anani1Karim El-Kersh2Corresponding author. Division of Pulmonary, Critical Care, and Sleep Medicine, University of Nebraska Medical Center, 982465 Nebraska Medical Center, Omaha, NE, 68198-2465, USA.; University of Nebraska Medical Center, Omaha, NE, USAUniversity of Nebraska Medical Center, Omaha, NE, USAUniversity of Nebraska Medical Center, Omaha, NE, USAFibrosing mediastinitis (FM) is a heterogeneous disease characterized by sclerosing fibrosis of mediastinal structures. Pulmonary hypertension (PH) may complicate the course of the disease and can contribute significantly to the morbidity of FM. Due to the rarity and complexity of the disease, evidence-based guidelines are not currently available, and the optimal treatment approach is unknown. Management approaches should be individualized, and current techniques are often unsatisfactory. Here, we present two cases of PH complicating FM that were managed using pulmonary artery vasodilator therapy with excellent hemodynamic response.http://www.sciencedirect.com/science/article/pii/S2213007124000297Fibrosing mediastinitisMediastinal fibrosisSclerosing mediastinitisPulmonary hypertensionPulmonary vasodilators |
| spellingShingle | Daniel Van Kalsbeek Abedel Rahman Anani Karim El-Kersh Pulmonary artery vasodilators for treatment of pulmonary hypertension complicating fibrosing mediastinitis Respiratory Medicine Case Reports Fibrosing mediastinitis Mediastinal fibrosis Sclerosing mediastinitis Pulmonary hypertension Pulmonary vasodilators |
| title | Pulmonary artery vasodilators for treatment of pulmonary hypertension complicating fibrosing mediastinitis |
| title_full | Pulmonary artery vasodilators for treatment of pulmonary hypertension complicating fibrosing mediastinitis |
| title_fullStr | Pulmonary artery vasodilators for treatment of pulmonary hypertension complicating fibrosing mediastinitis |
| title_full_unstemmed | Pulmonary artery vasodilators for treatment of pulmonary hypertension complicating fibrosing mediastinitis |
| title_short | Pulmonary artery vasodilators for treatment of pulmonary hypertension complicating fibrosing mediastinitis |
| title_sort | pulmonary artery vasodilators for treatment of pulmonary hypertension complicating fibrosing mediastinitis |
| topic | Fibrosing mediastinitis Mediastinal fibrosis Sclerosing mediastinitis Pulmonary hypertension Pulmonary vasodilators |
| url | http://www.sciencedirect.com/science/article/pii/S2213007124000297 |
| work_keys_str_mv | AT danielvankalsbeek pulmonaryarteryvasodilatorsfortreatmentofpulmonaryhypertensioncomplicatingfibrosingmediastinitis AT abedelrahmananani pulmonaryarteryvasodilatorsfortreatmentofpulmonaryhypertensioncomplicatingfibrosingmediastinitis AT karimelkersh pulmonaryarteryvasodilatorsfortreatmentofpulmonaryhypertensioncomplicatingfibrosingmediastinitis |