Prevalence and risk factors of allergic rhinitis among Chinese adults: A nationwide representative cross-sectional study
Background: The prevalence of allergic rhinitis (AR) has been increasing steadily worldwide, especially in countries with increasing industrialization such as China. However, available evidence regarding AR prevalence among Chinese adults is scarce and limited to regional data collected in earlier y...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-03-01
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| Series: | World Allergy Organization Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1939455123000042 |
| _version_ | 1797850342251036672 |
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| author | Xiao Zhang, PhD Mei Zhang, PhD Haijing Sui, PhD Chun Li, MD Zhengjing Huang, MD Bo Liu, PhD Xiaoting Song, MD Shuanglu Liao, PhD Miao Yu, MD Tingting Luan, MD Torsten Zuberbier, PhD Limin Wang, MPH Zuotao Zhao, PhD Jing Wu, PhD |
| author_facet | Xiao Zhang, PhD Mei Zhang, PhD Haijing Sui, PhD Chun Li, MD Zhengjing Huang, MD Bo Liu, PhD Xiaoting Song, MD Shuanglu Liao, PhD Miao Yu, MD Tingting Luan, MD Torsten Zuberbier, PhD Limin Wang, MPH Zuotao Zhao, PhD Jing Wu, PhD |
| author_sort | Xiao Zhang, PhD |
| collection | DOAJ |
| description | Background: The prevalence of allergic rhinitis (AR) has been increasing steadily worldwide, especially in countries with increasing industrialization such as China. However, available evidence regarding AR prevalence among Chinese adults is scarce and limited to regional data collected in earlier years. We therefore aimed to provide a more recent and robust estimate of AR prevalence using a nationwide representative cross-sectional study in China. Methods: Data of 184 326 participants aged 18 years or older were obtained from the China Chronic Disease and Risk Factor Surveillance conducted in 2018–2019. AR was determined by self-reported sneezing, nasal itching, obstruction, or rhinorrhea symptoms for at least 1 h in the absence of a cold or flu within the last 12 months. Multivariable logistic model was used to examine the risk factors of AR, and a possible non-linear relationship was further tested by restricted cubic spline. Potential additive interactions of risk factors with sex, residence, and geographic region were assessed by relative excess risk due to interaction (RERI). Results: The weighted prevalence of AR was 8.1% (95% confidence interval [CI], 7.4%–8.7%), of whom 23.7% (95% CI, 21.3%–26.0%) were aware of their diagnosis. Increased odds of AR were associated with younger age, men, living in urban area or north region, more education, smoking, underweight, and higher income. Despite the nonsignificant linear trend, the spline regression demonstrated a non-linear association between AR and sleep duration, with higher odds at both ends. Additionally, the observed associations were generally stronger among men and people living in urban area and north region, with significant RERI ranging from 0.07 (95% CI, 0.00–0.14) to 0.40 (95% CI, 0.12–0.67). Conclusions: AR is prevalent in China and the associated factors and interactions are helpful to design targeted preventive strategies towards certain subpopulations. The low awareness of AR calls for a national effort on AR screening. |
| first_indexed | 2024-04-09T18:58:50Z |
| format | Article |
| id | doaj.art-fc6aec11abc74004b7b0133d4ee7ebca |
| institution | Directory Open Access Journal |
| issn | 1939-4551 |
| language | English |
| last_indexed | 2024-04-09T18:58:50Z |
| publishDate | 2023-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | World Allergy Organization Journal |
| spelling | doaj.art-fc6aec11abc74004b7b0133d4ee7ebca2023-04-09T05:46:08ZengElsevierWorld Allergy Organization Journal1939-45512023-03-01163100744Prevalence and risk factors of allergic rhinitis among Chinese adults: A nationwide representative cross-sectional studyXiao Zhang, PhD0Mei Zhang, PhD1Haijing Sui, PhD2Chun Li, MD3Zhengjing Huang, MD4Bo Liu, PhD5Xiaoting Song, MD6Shuanglu Liao, PhD7Miao Yu, MD8Tingting Luan, MD9Torsten Zuberbier, PhD10Limin Wang, MPH11Zuotao Zhao, PhD12Jing Wu, PhD13National Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, ChinaNational Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, ChinaDepartment of Otorhinolaryngology Head and Neck Surgery, Peking University First Hospital, Beijing, ChinaNational Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, ChinaNational Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, ChinaDepartment of Dermatology and Venerology, Peking University First Hospital, Beijing, ChinaDepartment of Dermatology and Venerology, Peking University First Hospital, Beijing, ChinaDepartment of Dermatology and Venerology, Peking University First Hospital, Beijing, ChinaDepartment of Dermatology and Venerology, Peking University First Hospital, Beijing, ChinaDepartment of Dermatology and Venerology, Peking University First Hospital, Beijing, ChinaDermatological Allergology, Allergie-Centrum-Charité, Department of Dermatology, Venereology and Allergy, Charité – Universitätsmedizin Berlin, GermanyNational Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, ChinaDepartment of Dermatology and Venerology, Peking University First Hospital, Beijing, ChinaNational Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China; Corresponding author. National Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, 27 Nanwei Road, Beijing, China.Background: The prevalence of allergic rhinitis (AR) has been increasing steadily worldwide, especially in countries with increasing industrialization such as China. However, available evidence regarding AR prevalence among Chinese adults is scarce and limited to regional data collected in earlier years. We therefore aimed to provide a more recent and robust estimate of AR prevalence using a nationwide representative cross-sectional study in China. Methods: Data of 184 326 participants aged 18 years or older were obtained from the China Chronic Disease and Risk Factor Surveillance conducted in 2018–2019. AR was determined by self-reported sneezing, nasal itching, obstruction, or rhinorrhea symptoms for at least 1 h in the absence of a cold or flu within the last 12 months. Multivariable logistic model was used to examine the risk factors of AR, and a possible non-linear relationship was further tested by restricted cubic spline. Potential additive interactions of risk factors with sex, residence, and geographic region were assessed by relative excess risk due to interaction (RERI). Results: The weighted prevalence of AR was 8.1% (95% confidence interval [CI], 7.4%–8.7%), of whom 23.7% (95% CI, 21.3%–26.0%) were aware of their diagnosis. Increased odds of AR were associated with younger age, men, living in urban area or north region, more education, smoking, underweight, and higher income. Despite the nonsignificant linear trend, the spline regression demonstrated a non-linear association between AR and sleep duration, with higher odds at both ends. Additionally, the observed associations were generally stronger among men and people living in urban area and north region, with significant RERI ranging from 0.07 (95% CI, 0.00–0.14) to 0.40 (95% CI, 0.12–0.67). Conclusions: AR is prevalent in China and the associated factors and interactions are helpful to design targeted preventive strategies towards certain subpopulations. The low awareness of AR calls for a national effort on AR screening.http://www.sciencedirect.com/science/article/pii/S1939455123000042Allergic rhinitisChinese adultsNationwide representativeRisk factorsAdditive interaction |
| spellingShingle | Xiao Zhang, PhD Mei Zhang, PhD Haijing Sui, PhD Chun Li, MD Zhengjing Huang, MD Bo Liu, PhD Xiaoting Song, MD Shuanglu Liao, PhD Miao Yu, MD Tingting Luan, MD Torsten Zuberbier, PhD Limin Wang, MPH Zuotao Zhao, PhD Jing Wu, PhD Prevalence and risk factors of allergic rhinitis among Chinese adults: A nationwide representative cross-sectional study World Allergy Organization Journal Allergic rhinitis Chinese adults Nationwide representative Risk factors Additive interaction |
| title | Prevalence and risk factors of allergic rhinitis among Chinese adults: A nationwide representative cross-sectional study |
| title_full | Prevalence and risk factors of allergic rhinitis among Chinese adults: A nationwide representative cross-sectional study |
| title_fullStr | Prevalence and risk factors of allergic rhinitis among Chinese adults: A nationwide representative cross-sectional study |
| title_full_unstemmed | Prevalence and risk factors of allergic rhinitis among Chinese adults: A nationwide representative cross-sectional study |
| title_short | Prevalence and risk factors of allergic rhinitis among Chinese adults: A nationwide representative cross-sectional study |
| title_sort | prevalence and risk factors of allergic rhinitis among chinese adults a nationwide representative cross sectional study |
| topic | Allergic rhinitis Chinese adults Nationwide representative Risk factors Additive interaction |
| url | http://www.sciencedirect.com/science/article/pii/S1939455123000042 |
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