Type I Interferons, Autophagy and Host Metabolism in Leprosy

Type I Interferons, Autophagy and Host Metabolism in Leprosy

For those with leprosy, the extent of host infection by Mycobacterium leprae and the progression of the disease depend on the ability of mycobacteria to shape a safe environment for its replication during early interaction with host cells. Thus, variations in key genes such as those in pattern recog...

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Bibliographic Details
Main Authors: Thiago Gomes Toledo Pinto, Leonardo Ribeiro Batista-Silva, Rychelle Clayde Affonso Medeiros, Flávio Alves Lara, Milton Ozório Moraes
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Immunology
Subjects:
leprosy
tuberculosis
innate immunity
autophagy
type I interferon
metabolism
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00806/full

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