An update on the development of novel antifungal agents for eumycetoma
Eumycetoma, a chronic subcutaneous mycosis, responds poorly to the available antifungal treatments and patients often require extensive surgical resection or amputation of the affected limb. More effective treatments are needed for eumycetoma. This article will describe some of the approaches being...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-05-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2023.1165273/full |
| _version_ | 1797824479721684992 |
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| author | David J. Chandler David J. Chandler Alexandro Bonifaz Wendy W. J. van de Sande |
| author_facet | David J. Chandler David J. Chandler Alexandro Bonifaz Wendy W. J. van de Sande |
| author_sort | David J. Chandler |
| collection | DOAJ |
| description | Eumycetoma, a chronic subcutaneous mycosis, responds poorly to the available antifungal treatments and patients often require extensive surgical resection or amputation of the affected limb. More effective treatments are needed for eumycetoma. This article will describe some of the approaches being used to develop and evaluate new treatments for eumycetoma, summarise the latest developments and discuss the challenges that lie ahead. |
| first_indexed | 2024-03-13T10:39:36Z |
| format | Article |
| id | doaj.art-fc70c523527246318702e5e832e4666c |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-03-13T10:39:36Z |
| publishDate | 2023-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-fc70c523527246318702e5e832e4666c2023-05-18T05:13:33ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122023-05-011410.3389/fphar.2023.11652731165273An update on the development of novel antifungal agents for eumycetomaDavid J. Chandler0David J. Chandler1Alexandro Bonifaz2Wendy W. J. van de Sande3Department of Global Health and Infection, Brighton and Sussex Medical School, Brighton, United KingdomDermatology Department, Brighton General Hospital, University Hospitals Sussex NHS Foundation Trust, Brighton, United KingdomHospital General de México “Dr. Eduardo Liceaga”, Mexico City, MexicoErasmus MC, University Medical Center Rotterdam, Department of Medical Microbiology and Infectious Diseases, Rotterdam, NetherlandsEumycetoma, a chronic subcutaneous mycosis, responds poorly to the available antifungal treatments and patients often require extensive surgical resection or amputation of the affected limb. More effective treatments are needed for eumycetoma. This article will describe some of the approaches being used to develop and evaluate new treatments for eumycetoma, summarise the latest developments and discuss the challenges that lie ahead.https://www.frontiersin.org/articles/10.3389/fphar.2023.1165273/fulleumycetomaNeglected Tropical Disease (NTD)mycologyskin NTDsMadurella mycetomatis |
| spellingShingle | David J. Chandler David J. Chandler Alexandro Bonifaz Wendy W. J. van de Sande An update on the development of novel antifungal agents for eumycetoma Frontiers in Pharmacology eumycetoma Neglected Tropical Disease (NTD) mycology skin NTDs Madurella mycetomatis |
| title | An update on the development of novel antifungal agents for eumycetoma |
| title_full | An update on the development of novel antifungal agents for eumycetoma |
| title_fullStr | An update on the development of novel antifungal agents for eumycetoma |
| title_full_unstemmed | An update on the development of novel antifungal agents for eumycetoma |
| title_short | An update on the development of novel antifungal agents for eumycetoma |
| title_sort | update on the development of novel antifungal agents for eumycetoma |
| topic | eumycetoma Neglected Tropical Disease (NTD) mycology skin NTDs Madurella mycetomatis |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2023.1165273/full |
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