Deptor Enhances Triple-Negative Breast Cancer Metastasis and Chemoresistance through Coupling to Survivin Expression

Deptor Enhances Triple-Negative Breast Cancer Metastasis and Chemoresistance through Coupling to Survivin Expression

Transforming growth factor–β (TGF-β) functions to suppress tumorigenesis in normal mammary tissues and early-stage breast cancers and, paradoxically, acts to promote the metastasis and chemoresistance in late-stage breast cancers, particularly triple-negative breast cancers (TNBCs). Precisely how TG...

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Bibliographic Details
Main Authors: Jenny G. Parvani, Gangarao Davuluri, Michael K. Wendt, Christine Espinosa, Maozhen Tian, David Danielpour, Khalid Sossey-Alaoui, William P. Schiemann
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558615000299

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