PML Nuclear bodies: the cancer connection and beyond

PML Nuclear bodies: the cancer connection and beyond

ABSTRACTPromyelocytic leukemia (PML) nuclear bodies, membrane-less organelles in the nucleus, play a crucial role in cellular homeostasis. These dynamic structures result from the assembly of scaffolding PML proteins and various partners. Recent crystal structure analyses revealed essential self-int...

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Bibliographic Details
Main Authors:	Majdouline Abou-Ghali, Valérie Lallemand-Breitenbach
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2024-12-01
Series:	Nucleus
Subjects:	Nuclear bodies oxidative stress PML post-translational modifications senescence SUMO
Online Access:	https://www.tandfonline.com/doi/10.1080/19491034.2024.2321265

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