A Case of Severe Chronic Multifocal Osteomyelitis of the Skull Caused by Klebsiella pneumoniae in Mali
Ke Xu,1,2 Dara Charles,3 Salami Ismael,3 Jun Zhang4 1Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, People’s Republic of China; 2Laboratory and Anatomical Pathology Department of...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2023-09-01
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| Series: | Infection and Drug Resistance |
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| Online Access: | https://www.dovepress.com/a-case-of-severe-chronic-multifocal-osteomyelitis-of-the-skull-caused--peer-reviewed-fulltext-article-IDR |
| _version_ | 1797685543085015040 |
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| author | Xu K Charles D Ismael S Zhang J |
| author_facet | Xu K Charles D Ismael S Zhang J |
| author_sort | Xu K |
| collection | DOAJ |
| description | Ke Xu,1,2 Dara Charles,3 Salami Ismael,3 Jun Zhang4 1Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, People’s Republic of China; 2Laboratory and Anatomical Pathology Department of the Mali Hospital, Bamako, Mali; 3Neurosurgery Department of the Mali Hospital, Bamako, Mali; 4Department of Orthopedics, Zhejiang Provincial People’s Hospital Bijie Hospital, Bijie, Guizhou, People’s Republic of ChinaCorrespondence: Jun Zhang, Department of Orthopedics, Zhejiang Provincial People’s Hospital Bijie Hospital, 112 Guanghui Road, Bijie, Guizhou, 551700, People’s Republic of China, Tel +86-13868140717, Fax +86-857-8294072, Email spinezhangjun@aliyun.comAbstract: Highly invasive infections caused by Klebsiella pneumonia, which includes bacteremia, liver abscess, meningitis, septic arthritis, and osteomyelitis, in not commonly seen in adult immunocompetent and immunocompromised patients. Here, we report an adult case of chronic multifocal osteomyelitis with severe cranial involvement caused by Klebsiella pneumonia. The patient has a 5-year history of orbital abscess and multiple scalp traumas. CT scan showed right temporal and periorbital osteolysis, multiple parietal osteolysis. The pus was collected twice and routine culture was positive for Klebsiella pneumoniae. Good clinical outcome was achieved with debridement and antibiotic treatment. Microbiologists and clinicians should promptly perform bacteriological cultures on biopsy specimens to facilitate diagnosis when imaging or intraoperative findings of bone infection are suspected, especially in the Mali population.Keywords: osteomyelitis, skull, Klebsiella pneumoniae, multifocal |
| first_indexed | 2024-03-12T00:45:42Z |
| format | Article |
| id | doaj.art-fc7429b1ff9c4676bf4d7b84cc8b6815 |
| institution | Directory Open Access Journal |
| issn | 1178-6973 |
| language | English |
| last_indexed | 2024-03-12T00:45:42Z |
| publishDate | 2023-09-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Infection and Drug Resistance |
| spelling | doaj.art-fc7429b1ff9c4676bf4d7b84cc8b68152023-09-14T19:09:01ZengDove Medical PressInfection and Drug Resistance1178-69732023-09-01Volume 166139614386641A Case of Severe Chronic Multifocal Osteomyelitis of the Skull Caused by Klebsiella pneumoniae in MaliXu KCharles DIsmael SZhang JKe Xu,1,2 Dara Charles,3 Salami Ismael,3 Jun Zhang4 1Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, People’s Republic of China; 2Laboratory and Anatomical Pathology Department of the Mali Hospital, Bamako, Mali; 3Neurosurgery Department of the Mali Hospital, Bamako, Mali; 4Department of Orthopedics, Zhejiang Provincial People’s Hospital Bijie Hospital, Bijie, Guizhou, People’s Republic of ChinaCorrespondence: Jun Zhang, Department of Orthopedics, Zhejiang Provincial People’s Hospital Bijie Hospital, 112 Guanghui Road, Bijie, Guizhou, 551700, People’s Republic of China, Tel +86-13868140717, Fax +86-857-8294072, Email spinezhangjun@aliyun.comAbstract: Highly invasive infections caused by Klebsiella pneumonia, which includes bacteremia, liver abscess, meningitis, septic arthritis, and osteomyelitis, in not commonly seen in adult immunocompetent and immunocompromised patients. Here, we report an adult case of chronic multifocal osteomyelitis with severe cranial involvement caused by Klebsiella pneumonia. The patient has a 5-year history of orbital abscess and multiple scalp traumas. CT scan showed right temporal and periorbital osteolysis, multiple parietal osteolysis. The pus was collected twice and routine culture was positive for Klebsiella pneumoniae. Good clinical outcome was achieved with debridement and antibiotic treatment. Microbiologists and clinicians should promptly perform bacteriological cultures on biopsy specimens to facilitate diagnosis when imaging or intraoperative findings of bone infection are suspected, especially in the Mali population.Keywords: osteomyelitis, skull, Klebsiella pneumoniae, multifocalhttps://www.dovepress.com/a-case-of-severe-chronic-multifocal-osteomyelitis-of-the-skull-caused--peer-reviewed-fulltext-article-IDRosteomyelitisskullklebsiella pneumoniaemultifocal |
| spellingShingle | Xu K Charles D Ismael S Zhang J A Case of Severe Chronic Multifocal Osteomyelitis of the Skull Caused by Klebsiella pneumoniae in Mali Infection and Drug Resistance osteomyelitis skull klebsiella pneumoniae multifocal |
| title | A Case of Severe Chronic Multifocal Osteomyelitis of the Skull Caused by Klebsiella pneumoniae in Mali |
| title_full | A Case of Severe Chronic Multifocal Osteomyelitis of the Skull Caused by Klebsiella pneumoniae in Mali |
| title_fullStr | A Case of Severe Chronic Multifocal Osteomyelitis of the Skull Caused by Klebsiella pneumoniae in Mali |
| title_full_unstemmed | A Case of Severe Chronic Multifocal Osteomyelitis of the Skull Caused by Klebsiella pneumoniae in Mali |
| title_short | A Case of Severe Chronic Multifocal Osteomyelitis of the Skull Caused by Klebsiella pneumoniae in Mali |
| title_sort | case of severe chronic multifocal osteomyelitis of the skull caused by klebsiella pneumoniae in mali |
| topic | osteomyelitis skull klebsiella pneumoniae multifocal |
| url | https://www.dovepress.com/a-case-of-severe-chronic-multifocal-osteomyelitis-of-the-skull-caused--peer-reviewed-fulltext-article-IDR |
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