The relation of body mass index, body height, and parity to pyelonephritis: A nationwide population-based cohort study of over one million parous women (1997-2018)
Objectives: We aimed to explore the association between various physiological factors and pyelonephritis in parous women. Methods: Swedish nationwide registers were used to identify 1,073,467 parous women aged 15-50 years. The study period began in 1997 and ended in 2018, or at the first incidence o...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-12-01
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| Series: | International Journal of Infectious Diseases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971222005616 |
| _version_ | 1811292759766597632 |
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| author | Filip Jansåker Per-Ola Forsberg Xinjun Li Kristina Sundquist |
| author_facet | Filip Jansåker Per-Ola Forsberg Xinjun Li Kristina Sundquist |
| author_sort | Filip Jansåker |
| collection | DOAJ |
| description | Objectives: We aimed to explore the association between various physiological factors and pyelonephritis in parous women. Methods: Swedish nationwide registers were used to identify 1,073,467 parous women aged 15-50 years. The study period began in 1997 and ended in 2018, or at the first incidence of pyelonephritis, death, or emigration. Cox proportional hazards methods were used to determine hazard ratios (HRs) and 95% confidence intervals (CIs) of pyelonephritis in relation to body mass index (BMI) and body height adjusted for age, parity, and individual-level sociodemographic variables. Results: A total of 21,625 women (2.0%) were diagnosed with pyelonephritis during follow-up. In the fully adjusted model, low BMI (<18.5) was associated with pyelonephritis (HR 1.13, 95% CI 1.06-1.21). Parity and certain sociodemographic characteristics were also independently associated with pyelonephritis. Body height <161 cm was associated with pyelonephritis (HR 1.12, 95% CI 1.09-1.16) in all but the fully adjusted model. Conclusion: Low BMI and body height seem to be associated with uncomplicated pyelonephritis. More research is needed to verify these findings and identify possible mechanisms. |
| first_indexed | 2024-04-13T04:50:15Z |
| format | Article |
| id | doaj.art-fc78959322fe4c29be552a2193656df5 |
| institution | Directory Open Access Journal |
| issn | 1201-9712 |
| language | English |
| last_indexed | 2024-04-13T04:50:15Z |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj.art-fc78959322fe4c29be552a2193656df52022-12-22T03:01:42ZengElsevierInternational Journal of Infectious Diseases1201-97122022-12-011256773The relation of body mass index, body height, and parity to pyelonephritis: A nationwide population-based cohort study of over one million parous women (1997-2018)Filip Jansåker0Per-Ola Forsberg1Xinjun Li2Kristina Sundquist3Center for Primary Health Care Research, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden; Department of Clinical Microbiology, Center of Diagnostic Investigations, Rigshospitalet, Copenhagen University Hospital, Denmark; Corresponding author at: Center for Primary Health Care Research, Clinical Research Center (CRC), Jan Waldenströms gata 35, Skåne, University Hospital, 205 02, Malmö, Sweden.Center for Primary Health Care Research, Department of Clinical Sciences Malmö, Lund University, Malmö, SwedenCenter for Primary Health Care Research, Department of Clinical Sciences Malmö, Lund University, Malmö, SwedenCenter for Primary Health Care Research, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden; Department of Family Medicine and Community Health, Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, New York, USAObjectives: We aimed to explore the association between various physiological factors and pyelonephritis in parous women. Methods: Swedish nationwide registers were used to identify 1,073,467 parous women aged 15-50 years. The study period began in 1997 and ended in 2018, or at the first incidence of pyelonephritis, death, or emigration. Cox proportional hazards methods were used to determine hazard ratios (HRs) and 95% confidence intervals (CIs) of pyelonephritis in relation to body mass index (BMI) and body height adjusted for age, parity, and individual-level sociodemographic variables. Results: A total of 21,625 women (2.0%) were diagnosed with pyelonephritis during follow-up. In the fully adjusted model, low BMI (<18.5) was associated with pyelonephritis (HR 1.13, 95% CI 1.06-1.21). Parity and certain sociodemographic characteristics were also independently associated with pyelonephritis. Body height <161 cm was associated with pyelonephritis (HR 1.12, 95% CI 1.09-1.16) in all but the fully adjusted model. Conclusion: Low BMI and body height seem to be associated with uncomplicated pyelonephritis. More research is needed to verify these findings and identify possible mechanisms.http://www.sciencedirect.com/science/article/pii/S1201971222005616Body mass indexHeightParityPyelonephritisUrinary tract infection |
| spellingShingle | Filip Jansåker Per-Ola Forsberg Xinjun Li Kristina Sundquist The relation of body mass index, body height, and parity to pyelonephritis: A nationwide population-based cohort study of over one million parous women (1997-2018) International Journal of Infectious Diseases Body mass index Height Parity Pyelonephritis Urinary tract infection |
| title | The relation of body mass index, body height, and parity to pyelonephritis: A nationwide population-based cohort study of over one million parous women (1997-2018) |
| title_full | The relation of body mass index, body height, and parity to pyelonephritis: A nationwide population-based cohort study of over one million parous women (1997-2018) |
| title_fullStr | The relation of body mass index, body height, and parity to pyelonephritis: A nationwide population-based cohort study of over one million parous women (1997-2018) |
| title_full_unstemmed | The relation of body mass index, body height, and parity to pyelonephritis: A nationwide population-based cohort study of over one million parous women (1997-2018) |
| title_short | The relation of body mass index, body height, and parity to pyelonephritis: A nationwide population-based cohort study of over one million parous women (1997-2018) |
| title_sort | relation of body mass index body height and parity to pyelonephritis a nationwide population based cohort study of over one million parous women 1997 2018 |
| topic | Body mass index Height Parity Pyelonephritis Urinary tract infection |
| url | http://www.sciencedirect.com/science/article/pii/S1201971222005616 |
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